3SQD,3K05,3PC8


Conserved Protein Domain Family
BRCT_2
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pfam16589: BRCT_2 (This model is not part of the current CDD release)
BRCT domain
This BRCT domain, a BRCA1 C-terminus region, is found on many RAP1 proteins, usually at the very N-terminus. The function in human at least of a BRCT is to contribute to the heterogeneity of the telomere DNA length, but that may not be its general function, which remains unknown.
Links
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Statistics
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PSSM-Id: 522424
Aligned: 154 rows
Threshold Bit Score: 44.608
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3SQD_A        121 PLFKA------KYFY-----ITPGI-C----PSLSTMKAIVECAGGKVLSKQps--frKlmehkqnsslseiILISCEND 182  human
EGO01942      412 QTFLSrsg-rpFRFF-----VQVDLqG------RHGIVMAIKRNQGKIVNNItda-dyV-------------ILFTRSkt 465 
XP_007390545  381 GLFVDrkg-rpIPIY-----VQh-------aKWRNKYVPDIQKFGGKIVANIada-dyA-------------VLFTQALG 433 
XP_001828669  347 GLF-Srng-apISFF-----IQIDHaK------RNSLVQIVKTRGGTIVADVkea-dfA-------------ILYSAAPH 399 
ESK97910       83 VVFVTqdg-npLTFF-----VQMEVkN------RQTIISKIRKHGGLIKVTQeea-dyS-------------ILYPGSKT 136 
XP_001873168  392 GIFSTke--ggLSFF-----VQIDLgN------RLRIVTAIKKNGGKITNNHtta-dyS-------------VLYSGSQK 444 
EMD42123      376 NLFVEdg--raLNFV-----VQIDTrN------RKEIIQTVKAGGGKIIADIdka-dyV-------------VLNPNSHS 428 
EEC17537       10 NLFTRydg-gpMCFS-----LIp---C----AERKEIREIIEYGGGMLVqpgv--nprA-------------IRLVPAGA 61  
XP_046437262  377 NLFRKesngdpIEFYmrrtrSCHHEnNleleGKCSKLKEQIEKCGGNFGETPhschsiE-------------LVFPEVIE 443 
XP_046437262   19 NLFRKdsngeaIDFYlrrtrLGRQDnVek-eEKFKKLKEQIKKCGGHLGEEPrgchaiE-------------LVFPEYIT 84  

3SQD_A        183 LHlc-----rEyfARGIDVHNAEFVLTGVLTQTL--DYESY 216  human
EGO01942      466 fp----glakEaqNVNKRPLQSSFVVDCVKEGVVl-DDAEY 501 
XP_007390545  434 swd----ylrTavEAGTPAVKALYITDCLAKGKLl-NSSAY 469 
XP_001828669  400 kmkdyerflkAaqAHNVPAVRGHFVEHCDRQEKLl-DHTEF 439 
ESK97910      137 fra----slkEaaATNAIAVNTSFINDCVKEETLl-DYTPY 172 
XP_001873168  445 QKtfld-llrStiDAGRPAVSANFIRDCVARETLidDPTPY 484 
EMD42123      429 frq----lleRaeNFQKHAVNAQFVFDCAEEQTLv-EPDGY 464 
EEC17537       62 t---------VsvNDRDPVFSTEFVRECSKRDLLl-PLRNF 92  
XP_046437262  444 DIdei----------dsDVFKAEYVEECIKCGDLl-DLENF 473 
XP_046437262   85 DIdgi----------dsDLFKAEYIEECMKCGDLl-DLEQF 114
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