7AO8


Conserved Protein Domain Family
MBDa
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pfam16564: MBDa (This model is not part of the current CDD release)
p55-binding region of Methyl-CpG-binding domain proteins MBD
MBDa is a second MBD domain of Methyl-CpG-binding domain proteins. region implicated in binding the RbAp46/48 (retinoblastoma protein-associated protein) homologue p55, which is one of the components of the MBD2-NuRD complex. The MBD2-NuRD complex is a nucleosome remodelling and deacetylation complex.
Links
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Statistics
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PSSM-Id: 522407
Aligned: 24 rows
Threshold Bit Score: 90.7971
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
7AO8_C        223 QRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPSNKVKSDP-QRMNEQPRQLFWEKRLQGLSA 292 human
7_pfamImport    1 QKKQELLIAKTNQRRVLRSELPTRLTSCIFPKPVTRIRSHLDNAVRRRPrDKSLEKPQQLCAYRRLQGPQA 71 
ELK12830        7 KKKREVHLAKTKRRHRERSALPMRLTSCIFKRRVTRITSHPGSEVRRRQwDETLEKPQQVCAYRRLQGLQA 77 
3_pfamImport    1 AKKRQLVLAMSKRRRRERTEHPMRLTSCIFKSAVTKVTAHPDNVVRRRQqEETLEKPQQMSAYRRLQGLQA 71 
5_pfamImport    1 EKKRQEILVKAKQRRRDRCLLPLRLTSCIFQKPVTRITSHPGNVVKRRPcEETLEKPQQAFAFRRLQGLQV 71 
10_pfamImport   1 EKKRQYYLDKSEQSHCDETPLPIRLTSCIFQRPVTRITSHPGNVVRHHLcKGTLE-PQQVCAFRRLQGLQA 70 
Q2KIS0          6 QRKHCDCGKVSKPKPGLNISIPLRMSSYIFKRPVTRITSHPSNEVRCYPwEETLDNPQQLYWQKRLQGLQA 76  cattle
Q3UXB0         32 ETQIVPKKIKAKHRTGVTSKDSMRMTSCIFAKPVTTITSYPENETRYRReEDKLTKPKQLCALKRLKKHQV 102 house mouse
2_pfamImport    1 KIRVAQSKTKTKRRSGGTFKDPLRRTSCIFPQPVTLITSYSENKTRYRRdEAKLQKPEQLCALQRLENLQV 71 
EHB04222       12 QKKQQVHAPKAKRRAAGGCVLPVRLTSCIFPRPVTLITDHPGNEVRCGPhEEKLEKPQQLCSSWRLQALKH 82
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