8WEN,4ON1


Conserved Protein Domain Family
fragilysinNterm

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pfam16376: fragilysinNterm 
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N-terminal domain of fragilysin
N-terminal domain of fragilysin, an extracellular metalloprotease toxin, which is primary virulence factor of B. fragilis, an oportunistic pathogen of human gut. The N-terminal domain of fragilysin inhibits fragilysin and is cleaved in a mature, virulent form.
Statistics
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PSSM-Id: 292986
Aligned: 4 rows
Threshold Bit Score: 251.456
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
8WEN_C  37 SIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTSFILGDEFAVLRFYR 116 Bacteroides fragilis
O68424  37 VLNLRSMDYEDLAGVLSKISNTEHTIMLQEGSELWTTSIKAIHGVEIEESNRPVYLFEGQDKDSINAILSQSYATIRLQR 116 Bacteroides fragilis
Q6UCA5  29 SIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKIQLDNENVRLFNGRDKDSTSFILGDEFAVLRFYR 108 Bacteroides fragilis
4ON1_A  20 VLNLRSMDYEDLAGVLSKISNTEHTIMLQEGSELWTTSIKAIHGVEIEESNRPVYLFEGQDKDSINAILSQSYATIRLQR 99  Bacteroides fragilis
8WEN_C 117 NGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRTRSAGKDLVSVKINIDKA 180 Bacteroides fragilis
O68424 117 GGDLIDYIVYKDKERMAEIANYYQNHYLSASSDTSDKIVVCNTGEDTRSGKSDIKNIRIDITKA 180 Bacteroides fragilis
Q6UCA5 109 NGESISYIAYKEAQMMNEIAEFYAAPFKKTRAINEKEAFECIYDSRTRSAGKDLVSVKINIDKA 172 Bacteroides fragilis
4ON1_A 100 GGDLIDYIVYKDKERMAEIANYYQNHYLSASSDTSDKIVVCNTGEDTRSGKSDIKNIRIDITKA 163 Bacteroides fragilis
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