Conserved Protein Domain Family
TM_PBP2_N

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pfam16296: TM_PBP2_N 
N-terminal of TM subunit in PBP-dependent ABC transporters
This family mainly consists of Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs, such as Binding-protein-dependent transport systems inner membrane component and Maltose transport permease MalF. It is around 580 residues in length and is mainly found in various species, such as Thermotoga, Dictyoglomus, Thermosipho, Fervidobacterium, Mesotoga and so on. The function of this family is unknown.
Statistics
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PSSM-Id: 495738
Aligned: 18 rows
Threshold Bit Score: 97.7925
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015868733  69 ILLFILTIYPMYYTLRTAFTNFGTGHLFTRQQVVQKLLTEYFYTPENPKEYDFSIFVNlkDYrptdDFVILFTDTEtGKQ 148 Kosmotoga
WP_014693349  90 IFLIIFQIFPVLYTAGTAFTNFGDGHRGNKAEAITAIQTASVTRVPGSTEYQLKILAK--GD----QLAFLITDPKtGKV 163 unclassified Ac...
1_pfamImport   1 LFLIAFQVFPVLYTASTAFTNFGDGHRGSKDDAIVAVQTASVKQVPGSTEYNLTIATK--GDpatgALTFLLSDPKtKDV 78 
WP_023362523  85 LFLIVFQLFPVLYTAATAFTNFSDGHRGDKQDAVVAIQTASVTRVPGSAEYALTVATT--GDpatgPLTFLVTDPGtRTV 162 Actinoplanes fr...
WP_014446252  98 LFLVVFQLFPVLYTASTAFTNFGDGHRGSKQDAIVAIQTSSVTRVPGSAEYALSIATQ--GDpatgPIVFLITDPAtKAV 175 Actinoplanes mi...
WP_015749776  85 VFLIVYQLFMMLFTAYLSFTNYGTGHLDSKDAAIVAIQASNVVPVEGGTEYAVVPIEQn------gTVSMLVTDPAtNQV 158 Nakamurella mul...
WP_011690611 112 LFLLVFQVFVVLFSGYIAFTNYGDGHNSTKDDAIAAIQLTAQKRVPDSPAYKAAVLTKg------sDFYLLFTDPD-GKA 184 unclassified Ar...
WP_013771466  99 LFLLVYQVFVVLYTGWTAFTNYGDGHNSTQADAVEAILVQNETRLPDSPSYPLTVILSg------dELGFAVVDTE-GEA 171 Cellulomonas fimi
WP_013839073 106 LFLLVFQVYVVGYTGYVAFTNYGDGHNSTKEQAVEALLAQNERRVEGSPAAPLTVVESda-----gELGFAVVDES-GDV 179 Isoptericola va...
WP_015882278  90 aFLLVFQIYVVFYTGYVAFTNYGDGHNSTKEQAVEALLVQNERRVEGSESFPLVVVSDg------gELGFAIVDAD-GDV 162 Beutenbergia ca...
WP_015868733 149 Y 149 Kosmotoga
WP_014693349 164 S 164 unclassified Actinoplanes
1_pfamImport  79 F 79 
WP_023362523 163 S 163 Actinoplanes friuliensis
WP_014446252 176 S 176 Actinoplanes missouriensis
WP_015749776 159 R 159 Nakamurella multipartita
WP_011690611 185 S 185 unclassified Arthrobacter
WP_013771466 172 Q 172 Cellulomonas fimi
WP_013839073 180 R 180 Isoptericola variabilis
WP_015882278 163 E 163 Beutenbergia cavernae
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