8X15


Conserved Protein Domain Family
SANT_DAMP1_like
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pfam16282: SANT_DAMP1_like (This model is not part of the current CDD release)
SANT/Myb-like domain of DAMP1
This domain, approximately 90 residues, is mainly found in DNA methyltransferase 1-associated protein 1 (DAMP1) that plays an important role in development and maintenace of genome integrity in various mammalia species. It mainly consists of tandem repeats of three alpha-helices that are arranged in a helix-turn-helix motif and shows a structual similarity with SANT domain and Myb DNA-binding domain, indicating it contains a putative DNA binding site.
Links
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Statistics
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PSSM-Id: 522275
Aligned: 98 rows
Threshold Bit Score: 105.246
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8X15_V       124 YPFARFNKTVQ---VP-VYSEQEYQLYLHDDAWTKAETDHLFDLSRRFDLRFVVIHDRYDHQq---------------FK 184 human
XP_002565779 134 YAFAKYNVKPR---LPrRYTDDEYNRHLQSDDWSREETDYLVGLVTEYDIRWVLIADRYDYQprmdtqpd-analvpaKH 209
EKV19781      66 YAFAKYNVKPR---LPrRYTDDEYTRHLTSDDWSREETDYLVDLVTDYDIRWVLIADRYDYQpqmdtkpd-anaivpaKH 141
XP_001271630 148 YSFAKYNVKAQ---VPrRYTDEEYNRHLKNDDWSRQETDYLMDLVEEYDLRWVVIADRYDFHpqpadsesnatalvpaKR 224
XP_041144587 125 YLFAKYNVKAR---VPrRYTDEEYNRHLKSDDWSRQETDYLMDLVEEYDLRWVVIADRYDFQphpvdaetnnsalvpaNQ 201
Q4WNY4       133 YPFAKYNVKPR---VPrRYTDEEYNRHLKSDDWSRQETDYLMDLVEEYDLRWVVIADRYDFQpqpidaeanatalvpaKQ 209 Aspergillus fum...
XP_002542396 139 YSFAKYNVKPQ---IPrRYTDEEYDKYLQSDFWRREETDYLMDLVEEFDLRWVLIADRYDYQpkipesesnstalvaaSK 215
XP_015700763 128 YPFAKYNVKVQ---VPkRYTDEQYNRYLKSHNWSREETDYLMEIVEEYDLRWVVIVDRYEYPpnprgaegdltalvstTK 204
CBJ32265     127 YAYARYNVKVDidnHL-RYSDEEYKQHLTEASWTKLETDHLVAMALKYDLRWPVIKDRYKC-----------------TP 188
Q0CLG4       126 YMFAKYNIKAR---VPnRYTDDEYNRHLKSDDWSREETDYLMDIVEEYDLRWVVIADRYDFQprsedstsnanalvpaKR 202 Aspergillus ter...

8X15_V       185 KRSVEDLKERYYHICAKLA 203 human
XP_002565779 210 HRTMEQMKARYYYIAATML 228
EKV19781     142 HRTMEQMKARYYKIAATML 160
XP_001271630 225 YRTMEQMKARYYFIAASML 243
XP_041144587 202 VRTMEHMKARYYFVAASML 220
Q4WNY4       210 YRTMEQMKARYYFIAASML 228 Aspergillus fumigatus Af293
XP_002542396 216 PRTMEEMKSRYYTVAGKML 234
XP_015700763 205 RRTMEEMKSRYYTVAANML 223
CBJ32265     189 DRPVQELQQRFYDVANRLQ 207
Q0CLG4       203 YRTMEQMKSRYYFVAASML 221 Aspergillus terreus NIH2624
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