Conserved Protein Domain Family
NuDC

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pfam16273: NuDC (This model is not part of the current CDD release)
Nuclear distribution C domain
This domain, approximately 40-50 residues in length, is mainly found in nuclear migration proteins in various Mammalia species. It may play a role not only in mitosis and cytokinesis, but also in interkinetic nuclear migration and neuronal migration during neocortical development.
Statistics
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PSSM-Id: 522269
Aligned: 19 rows
Threshold Bit Score: 42.0112
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ELW47669      96 TSETPGPQIKELTDEEAERLQLEIDQKKDAENHEAQVKNGSLDSSGKQEYLsifhceQEAEED-GEEEDEKDK 167
EDS29707     102 DQSAAAAAITELTDAEAEKMQRELEDAKKNKEVKEPAPAAAAAE-------------EEKTEK-DDDEEPEDK 160
XP_015462327  98 KELENEPRIKELTDEEAERLQTEIDQKKDKEEQKEKKDTESSAADTSDKA-------EKGSES-EGEEDEKDK 162
XP_006631335 101 TGEQNEPKIKELTDEEAAQLQSEIDQKKE-EAKKQESAPKNDAENSSDKVE------DKGSDS-EGEEDEKDK 165
XP_003227510 101 KQEESEPRIKELTDEEAERLQLEIDQKKEKKDSEAQSIPVESAENSMETPEs-----NKQDTD-EEEEDEKDK 167
3_pfamImport   1 QQEASGPQIKELTDEEAERLQLEIDQRKGKENSQGDGPAQPLNSSSNSSG-------KQEDDD-EEEEDEKDK 65 
O35685        96 KAETPGPQIKELTDEEAERLQLEIDQKKDAEDQEAQLKNGSLDSPGK----------QDAEDE-EDEEDEKDK 157 house mouse
XP_004850737  96 KAENSGPQIQELTDEEAERLQLELDKKKDAENHEAQLKNGSIGPPEK----------QESAED-EEEEDEKDK 157
XP_036770784  96 KSETSGPQIKELTDEEAERLQLEIDQKKDAESHEAQLKNGTLGSPGK----------QEAEEDeE-EEDEKDK 157 Chinese pangolin
XP_024998755  94 KQEANEPRIKELTDEEAERLQLEIDQKKEAQKEVNNVPVKSSEDDGDSSDS------NKQETD-DEEKDENDK 159 chicken
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