pfam16088: BORCS7 (This model is not part of the current CDD release)
BLOC-1-related complex sub-unit 7
This is a family of unknown function found in eukaryotes. Family members include BORCS7 (BLOC-1-related complex sub-unit 7) also known as Diaskedin (from the Ancient Greek 'diaskedazo', meaning 'to disperse') or C10orf32. It constitutes sub-unit 7 of the BORC complex (BLOC-one-related complex). BORC is a multisubunit complex that regulates the positioning of lysosomes at the cell periphery, and consequently affects cell migration. BORC associates with the lysosomal membrane, where it functions to recruit the small GTPase Arl8. This initiates a series of interactions that promote the microtubule-guided transport of lysosomes toward the cell periphery.
Jiyao W et al.(2023). "The conserved domain database in 2023.",