Conserved Protein Domain Family
JAKMIP_CC3
?
pfam16034: JAKMIP_CC3 (This model is not part of the current CDD release)
JAKMIP CC3 domain
This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.
Links
?
Statistics
?
PSSM-Id: 522151
Aligned: 7 rows
Threshold Bit Score: 183.923
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
XP_020562211  433 ERDRLVMSRKVRKKPCKLLNRN---VVETYFGFDEE-SVDSETSSLtSYNTDLTDRTPATPE----ED--LEE----NVS 498 
XP_009289287  411 ERDRLIINKKNRRKNIKLPKRH---VVETYFGFDEE-SVDSETSSLtSYNTDRTDYTPATPE----ED--LED----GFS 476 
XP_002710338  409 DREKLIRRRKHRRSSKPIKRP----VLDPFIGYDED-SMDSETSSMaSFRTDR---TPATPD----DD--LDE----GLA 470 
XP_002427661   20 ERDKIISALREAAEEKDKKLEDlimEYTKMKNNDYGnKLDLESTTD-STNHRGNLSSPSSPPlcngELcwTDN----FVN 94  
2_pfamImport    1 VKTVIVSEICKSGLTVWLWKSRdlcVIETFYGYDEEaSVDSDGSSL-SFHTDK------TPD----TE--PDE----SCA 63  
1_pfamImport    1 ERDMLLRYRRQESVKRKRTLKAc-rVIETFYGYDEEaCADSDGSSL-SFHTDQ------TPD----TE--PDEmgkgMVC 66  
XP_046796389  421 ERERLLRSKKQKKKILKPQKRH---VVETFFGFDEE-SLDSETSSVtSYNTDKTDRTPATPE----ED--LED----STP 486  chicken

XP_020562211  499 REESELRFRQLTREYQALQRAYALLQEQSGgSLDAEREARTREQLQMELSSCQSKITDLEKALAERGQDSKWVEEKQYLI 578 
XP_009289287  477 REEAELRFRQLTREYQALQRAYALLQETTG-PLDPERHCRTREQLQTELIGCQARIADLERSLAEKGQDSKWVEEKQNLI 555 
XP_002710338  471 AEESELRFRQLTKEYQALQRAYALLQEQTGgIIDAEREAKAQEQLQAEVQRYKAKIEDLEATLAQKGQDSHWVEDKQLFI 550 
XP_002427661   95 ANYHEPVYAQLLNDHRALQKTYNELRSKL------ESKGKELERLEEETRNATSQ------------NDNKNLQE----- 151 
2_pfamImport   64 REDTELRYRQLTQEYQALQRAYALLTETSGgPCDPEKEIKTREQLMSEIRRFQSRVSDLESALTQQGLDVTWVEEKQALF 143 
1_pfamImport   67 VREAEFRYCQLTQEYQALQRAYALLTEKSGvNYDAEKEIKTREHLLAEISQYQTKIADLESALKQQGLDVKWVEEKQALY 146 
XP_046796389  487 KEEAELRFCQLTREYQALQRAYALLQEQVGgTLDAEREARTREQLQADLLRCQAKIEDLEKALIEKGQDSKWVEEKQLLI 566  chicken

XP_020562211  579 RANQE------LHEKIHVLQQTESSLQAEVQDARDQNELLEFRVLELEE-RERRSP--AFN 630 
XP_009289287  556 RINQE------LREKIVSLEQCEIRLRSEVRDTLDQNELLEFRILELEE-RERRSP--AFN 607 
XP_002710338  551 KRNQE------LLEKIEKQEAENHRLQQELQDARDQNELLEFRNLELEE-RERRSP--PFN 602 
XP_002427661  152 --NHEnainliMAEQIRILKEREGQLIAEAEELREQRDLMEFRILELEEcRKEFLDkeVIR 210 
2_pfamImport  144 QRNQE------LVEKVRHMEGEEMRLKNDIQDIRDQNELLEFRILELEE-RERRSP----G 193 
1_pfamImport  147 QRNQQ------LVEKVKQMEGEELQLKNEIQDIRDQNELLEFRILELEE-RERRSP--AIN 198 
XP_046796389  567 RTNQE------LLEKIYRMEQEEHQLKNEMQDAKDQNELLEFRVLELEE-RERRSP--AFN 618  chicken
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap