2GRX


Conserved Protein Domain Family
TonB_N
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pfam16031: TonB_N (This model is not part of the current CDD release)
TonB polyproline region
TonB from Escherichia coli and its homologues are critical for the uptake of siderophores through the outer membrane of Gram-negative bacteria using chemiosmotic energy. The proline-rich segment of TonB exists in a PPII-like conformation. The result implies that the proline-rich segment of TonB possesses a length of more than 15 nm, sufficient to span the periplasm of Gram-negative bacteria.
Links
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Statistics
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PSSM-Id: 522149
Aligned: 5 rows
Threshold Bit Score: 33.5283
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2GRX_C               26 IELPAPAq-PISVTMVTPADL-EPPqavqpPPEPvVEPEPEpEPipE-----PPKEAPV-------VIEK--PKPKPKP- 88  Escheric...
WP_038668436         38 MSLPSAVeqPMTVMLVAPEPQqAPPveqppDPQPvAPEPEVaPQpvP-----EPEPEPVpep--paPVQV--PKPVPKP- 107 Sodalis ...
P02929               36 IELPAPAq-PISVTMVTPADL-EPPq----AVQP-PPEPVV--E--P-----EPEPEPIpeppkeaPVVIekPK--PKP- 96  Escheric...
1_pfamImport          4 KIQPEIEdtPLAVTMVNIAEF-AAPqpaaaAPEPvQETPAVpEEtpPvleetPPEPEELpe---------pvPVPVPEPv 73 
goetting:EBL_c19110  50 MQLPAPAr-AISISMVSPADL-EPP-----QTAP-APAPAV-AE--P-----EPEPEVLpeppkeaPVVIhkPKPKPKP- 112

2GRX_C               89 KPKPVKKVqe--qpKRDVKPVESRPAS-PFENt-----APARLTSSTATAATSKPVTSVAS----GPRAL 146 Escherichia coli
WP_038668436        108 KPKPKPER------HREIKPRTPKPETrPASPap--saPPVRPATAPVTSAPASSSVKSASs---APRAT 166 Sodalis praecaptivus
P02929               97 KPKPKPVKkvqeqpKRDVKPVESRPAS-PFENt-----APARLTSSTATAATSKPVTSVAS----GPRAL 156 Escherichia coli K-12
1_pfamImport         74 KPKPKPVKke--vkKPEVKKTQAPPDDkPFKSdeaalvANNAPVKSAPVASTPGLSTSA------GPKAL 135
goetting:EBL_c19110 113 KPKPKPVQkve-peKKPAKPVESRAES-PFDNpdstatTTSRPVSGTARPGPAAPVASTASpavgGPRAL 180
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