8H93,3V69


Conserved Protein Domain Family
MOEP19
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pfam16005: MOEP19 (This model is not part of the current CDD release)
KH-like RNA-binding domain
MOEP19 is a family of mammalian KH-like RNA-binding motifs. The family is expressed during early embryogenesis. It appears to effect an early form of molecular asymmetry within the murine oocyte cytoplasm. The family marks a defined cortical cytoplasmic domain in oocytes and provides evidence for mammalian oocyte polarity and a form of pre-patterning that persists in zygotes and early embryos through the morula stage.
Links
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Statistics
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PSSM-Id: 522135
Aligned: 24 rows
Threshold Bit Score: 89.6204
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8H93_C         31 TRPWWFPIQEVSNPLVLYMEAWVAERVIGTDQAEISEIEWMCQALLTVDSVNS-GNLAEITIFGQPSAQTRMKNILLNMA 109 house mouse
10_pfamImport   1 ILPWLNVLEDLIDPKVLEVPPWLLEPMFGPDRSRISFFEKVGKTMIELQTSES-SAHTEIVVYGDLTYRARTTWMLQCLA 79 
NP_001164726   10 IPPWVKVPEDLKDPEVLQVQTRLLEAMFGPDGSRIPYIEQVSKAMLELKALES-SDLTEVVVYGSYMYKLRTKWMLQSMA 88 
XP_235194      10 IPPWVKVPEDLKDPEVFQVHTLVLKSLFGPQGSRMPHIEQVSRAMFELKILES-SGLTEVLIYGSCNHKLRAKWMLQSMA 88 
XP_013848085   11 ILSWVGAPEDFTEPEVFQVQTRLLEALFGPEGSRIPYVEKVSKVMLEMKALES-SDLTEVMVYGPYLYKFRTKWMLQSMA 89 
3_pfamImport    1 QQPWWMVPENFDTPMVVYLEEEQEEQIFGHNDAHLRCIEVHSQTLIQLESWFTaRGQTRVTIVGPPRARQWLMDMIWSLG 80 
XP_004044335   10 KEPWWTLPENFHSPMVFHMEEDQEELIFGLDDTYLRCIELHSHTLIQLEKCFTaTGQTRVTVVGPPMAKQWLLLMFHCVG 89 
XP_004770790   32 TQQYWCKFKHFLKPSVLNVEARLLEKIFGPSRVLLPGFEREFKVVLQMRKPNS-EGKVEIFILGRRRYRKRAKRLIRILT 110
D3ZVV1         28 RLPKWFHVEYLEDPKKMYVEPTLVEIMFGKDGEHIPHVECTLHVLIHVNVWGP-EKQAEILIFGPPNFQKDVAQMLSNVA 106 Norway rat
P85965         11 IPPWVKVPEDLTDPEVFQVQSLVLKYLFGPQGSRMSHIEQVSQAMFELKNLESpEELIEVFIYGYQSIKVRAKWLLQSMA 90  house mouse

8H93_C        110 AWHKENE 116 house mouse
10_pfamImport  80 ERHRRQG 86 
NP_001164726   89 EWHRQRQ 95 
XP_235194      89 ERYRLRQ 95 
XP_013848085   90 EWHCQRQ 96 
3_pfamImport   81 NWDPYQQ 87 
XP_004044335   90 SQYSKCH 96 
XP_004770790  111 TKPRRKS 117
D3ZVV1        107 HFCRMKL 113 Norway rat
P85965         91 ERYHLRQ 97  house mouse
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