Conserved Protein Domain Family
Imm63
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pfam15599: Imm63 
Immunity protein 63
A predicted immunity protein with an alpha+beta fold and a conserved E+G and ExxY motifs. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbour of the toxin gene, which usually contains toxin domains of the Ntox40, Tox-CdiAC and Tox-ARC families. The protein is also found in poly-immunity loci in polymorphic toxin systems.
Links
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Statistics
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PSSM-Id: 495207
Aligned: 7 rows
Threshold Bit Score: 89.7675
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_013371050  52 KQGYTLQMYERGVQMLNKLTQDVEDVMYWIIEDTIHIIAhLNLLRKYK---------VDNQNThLKYTKEIMKELTTAMN 122 Paenibacillus p...
WP_011100990  47 GQRYHFVYSERGTENKHNVTDNLFEIAYWVISSITDTLA-IRYVRTRV---------LPNQSQ-RKIIFDKKLSLLSIVG 115 Lactiplantibaci...
2_pfamImport   1 DGSWHLMSRERGQVISDRVATDREEFVRIVAEQIAE----MRAHRLHE----------PGTPDfRRAAWQEQYDALGSVD 66 
Q8YAA5        42 QDGYMLYGYEHGKRNSEFKTTDFDEFKYEVFLHICWYMG-MEFELRHRkedierddnILETDT-RKIAFEKTLQLLKMVN 119 Listeria monocy...
WP_014803177  78 NQKYHYVILERGKESERRSTPDLEEFFYWIFKAITWSMA-VDFELSNR---------IIGEDC-RRMIFQKQSELLGALD 146 Turneriella parva
AAM87124      49 NNMYNYIYSERGYEFSRRVTKSLDELLYWIMSELAHKAA-FQYELDHR---------VEGRDG-RRIAFPKFIELMANMN 117
1_pfamImport   1 DGKFICARDERGCQIFRRETFSSDEVLHWILDGIISRII-TDSEDFRE---------INDVNCgRKKFLMERINLMERLS 70 

WP_013371050 123 NAfyeiggiyqeWHEANRRATLE 145 Paenibacillus polymyxa
WP_011100990 116 EN----------YKKAGEIEISE 128 Lactiplantibacillus plantarum
2_pfamImport  67 RG----------WARQWLDATRA 79 
Q8YAA5       120 PA----------WIDKAAIGYSN 132 Listeria monocytogenes
WP_014803177 147 QN----------WQRRFGSETAQ 159 Turneriella parva
AAM87124     118 SA----------WESEARHEIQK 130
1_pfamImport  71 PV----------WGKKAREESDE 83
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