Conserved Protein Domain Family
Ntox50

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pfam15542: Ntox50 
Bacterial toxin 50
A predicted RNase toxin found in bacterial polymorphic toxin systems that is proposed to adopt the BECR (Barnase-EndoU-ColicinE5/D-RelE) fold, and contains two conserved histidine, a serine, two lysine, and a threonine residue and a HxVP motif. In bacterial polymorphic toxin systems, the toxin is usually exported by the type 2, type 6, type 7, and MuF-type secretion systems.
Statistics
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PSSM-Id: 406083
Aligned: 20 rows
Threshold Bit Score: 95.9042
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Cthe_2476 358 YSIQHYNKHKEGTKQYEQYKqsrlkkgqteqSSLLISYDEAKEIIKKYAGTGVFSRD-RKGKWrnEEFVDV-DSIIGVVH 435
jgi:Lebu_0908 271 LNEGSQGKHDPNHRNYQSER-----------HKSEVSMDDAKNIFKKFKATGNFVQDpRSGNF--YEIIDTqGEYQGIYI 337
CDE11493      429 INQGKQDKHIIGSNNYIDGK-----------SYLTISKEKAQELINQYAGKGQLEFS-DSGKWnkKEIITV-KETIGVVK 495
CDC38506      157 INDGKQGKHIKGHNNYIEGR-----------SYIIISSEEVQKLINKYAGTGMLIRT-KNGKWakQEVITT-NTLIGYDV 223
jgi:Cphy_2969 422 IETGKQGKHIKGHNNYIEGR-----------SYLTITEKETQDLVNKYAGTGEIKRD-NRGNWnnKEVVDF-KKEIGISI 488
Q6D1R1         66 IHDGAQGKHIEGHNNYVEGK-----------SVI---DAKPQELLDNYHA-GNVNTS--RVINenKIKVDF-GDVNGTHK 127 Pectobacterium...
Q9K0F4        327 IHDGAQGKHISGHRNYIEGK-----------STLN-QNINPQELLNGIHSGAYPVIS---KGArgNPVVDF-GYPIGS-- 388 Neisseria meni...
Q1WQZ4        121 INPEKQALHMESTKLE--GK-----------SYLY-DSEDPQELLDKYAGKGHINKN-KKGLWdnREVVEV-DHIVGVDY 184 Lactobacillus ...
CDA71452      294 INHEKQAKHIKGCPEYIDGR-----------SYLTISEDKAQKIINEKSGTGSLVYD-RKGLWknKELIDC-DEIIGVDI 360
Q2FYW8         11 LNNVKQKRHILCTNEYNNKKnnss----llpSYTIIDSNESEKMTKKEFIDIPVLFD-DEGNFriKQVIDY-KKIIGKSY 84  Staphylococcus...
jgi:Cthe_2476 436 N-IDGTVTPTNRIQIKYGKNS-VHIVP 460
jgi:Lebu_0908 338 NnRRNERLITPKFKIHYSKKGlVHVVP 364
CDE11493      496 N--KNNEIKTNSFKIHYSKTG-THIVP 519
CDC38506      224 NdISGAETATKAFKIHYSNKG-THIVP 249
jgi:Cphy_2969 489 DnLTGIEYVTTKAKIHYSKKG-VHVVP 514
Q6D1R1        128 D-MNGTNTSTSWGLIHSRKNG-AHIVP 152 Pectobacterium atrosepticum
Q9K0F4        389 --DGKSGLSTNFGTIHSGKNG-VHIVP 412 Neisseria meningitidis serogroup B
Q1WQZ4        185 N----SGMKTRWIKIHHSKKR-THIVP 206 Lactobacillus salivarius UCC118
CDA71452      361 NkSTREETSTDKGTIHYSKSG-THLVP 386
Q2FYW8         85 --VNGKYIETKLGKVHYSKTG-FHVVP 108 Staphylococcus aureus subsp. aureus NCTC 8325
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