Conserved Protein Domain Family
CAAP1
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pfam15335: CAAP1 
Caspase activity and apoptosis inhibitor 1
CAAP1, or caspase activity and apoptosis inhibitor 1, is a family of eukaryotic proteins involved in the regulation of apoptosis. It modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop.
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Statistics
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PSSM-Id: 495017
Aligned: 23 rows
Threshold Bit Score: 66.8453
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_015200834  64 FRPISAYITDRQEMLEQCFRVLGETKLKKMLPEELKNCSFDEIKRLCLEQLEQISQRNLLQIL 126
XP_015795508  21 IEPLSRLINEPEKLIDEVFKIAAQYLPKDIVPASLKDIPTVELKKLCLEQLKKVEHQTLLNIL 83 
EEC20106       3 WYDLSAFVDQREQLLEESFQALSPDELGILTPVELQHIPMGELKALCLDELRKLPNERVLAIL 65 
3_pfamImport   1 EHDLAYYIHDRVELMHQIFSVLKPKELKAMAPDCVRNVSIDDLQELCTEELLGISSKRLLAIL 63 
Q16N62        32 IKPLGAFVDDRVELIRQAFTCLKPKEIKCLVPDFLQGKSIEFLQEQCLDEVLGISTKRLLSII 94  yellow fever mosquito
Q5TXA3        70 LKPLSAYVDDRLELIRQVFSCVKPKEIKYLLPDFLEGKSNDVIKERCLDELLGISTKRLHSII 132 Anopheles gambiae str. PEST
9_pfamImport   1 LHPLTFYIDDRVELIKQVFASLKPKTIKNLSPNFLKKQTLEEIEEKCLNELLGISSKRLRSII 63 
2_pfamImport   1 LFPLSHYANDPEQLIQQLFSVVRGKRLTRLIPPELKDMTFEELKADCLIQLLCMSKKRVLATL 63 
EDO36174      76 IHPLSHYVDNKEELHKQIFSIVPKKEIKNLLPEILKGMDLKELKGLCLEQLEIMSQKRLRHII 138
XP_019855178  15 PRGLDAYFDDRLSLLDQLFTILTQQDIHGLLPDILKGLKMKKIKELCLKELEKLDNDQLLSII 77  Amphimedon queenslandica
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