Conserved Protein Domain Family
SYCE1
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pfam15233: SYCE1 (This model is not part of the current CDD release)
Synaptonemal complex central element protein 1
This family of proteins includes synaptonemal complex central element protein 1, a component of the synaptonemal complex involved in meiosis, and synaptonemal complex central element protein 1-like, which may be involved in meiosis.
Links
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Statistics
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PSSM-Id: 521716
Aligned: 13 rows
Threshold Bit Score: 96.0979
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_015212673    1 MEDLMNKLRKLQKGKTALE--EELKEGESLKKTLKEELDALHTERSQLEKAYREkedacktLQYQCELKEDTNRGH-QLN 77  
2_pfamImport    1 KNLEPRIEDLVKKINKLQQ--AKKILSEELSEANEHSKSLQRELEKCSVFLLFL-------LETRKVMQFHCEETEiKRQ 71  
6_pfamImport    1 GKTVPRIEELVKKLKQLQQ--GKNAVDEELCEARKCREALQKELDKLSAESFHLeeiynkkKETLQLLQFQYKEREnEIK 78  
NP_001315633   23 SRAELKPEELITQLRKLQQ--VKKILEEEVTEVMLLKCARKQEEDALAAEALKLegtlnakEELNRSLQLKCEDLQlEAQ 100 
Q9D495         49 GSLEPRIEVLINRINEVQQ--AKKKASEELGEAQTVWDNLQKELDLLREEKVRLkdilnrkEETLRIMQLHCQEKEsEAQ 126  house mouse
3_pfamImport    1 GSLEPQIEDLINRINELQQ--AKKKSNEELGETQALWETLHRELDSLNGEKVHLeevlrkkQEALRILQLHCQRKEsEAQ 78  
5_pfamImport    1 GTLEPQIEDLIHRIYKLQQgpAKKKSGEELGETQALWEALNRELDSLNGENLHLeevlnkkQEALRILQQHRQAQEsGAP 80  
ELW62989      742 GSLEPQIEDLINRINELQQ--AKKKSSEELGEAHAVWEALHRELDSLNGEKVHLeevlskkQEALRILQLHCQEREsGAR 819 
8_pfamImport    1 GSLEPQIGDLINRINELQQ--AKK-ANEELGETQARREVLCKELDSLNGEKVHIeevlskkQGIYLLLHVPPSNPTsQKP 77  
Q5D525         45 GSLEPQIEDLIHRINELQQgpAKKRSSEELGEAQALQEAMHRELDSLNEERVHLeevlrkkQEAVSILKKHPQERDsDTP 124  house mouse
A8MT33         42 GSLEPQIEDLISRINDLQQ--AKKKSSEELRETHSLWEALHRELDSLNGEKVHLeevlgkkQEALRILQMHCQEKEsEAQ 119  human
Q8N0S2         47 GSLEPRVEVLINRINEVQQ--AKKKANKDLGEARTICEALQKELDSLHGEKVHLkeilskkQETLRILRLHCQEKEsEAH 124  human
NP_001137235   47 GSLEPRVEVLINRINEVQQ--AKKKANKDLGEARTICEALQKELDSLHGEKVHLkeilskkQETLRILRLHCQEKEsEAH 124  human

XP_015212673   78 SEHEQLLEEYTFKIQEAKLKHRKQRMKFENQLQQLLEDHKNMYSIYSPERLPV-EIEnAENANAQLLKAEQIKLL 151 
2_pfamImport   72 WQQKLNLECKQRIEAVTAKIQAEKRKQSKQRMEFEQLLEELMEKHKRLWELYV-RSR-DQPVADMKDSKERLLKE 144 
6_pfamImport   79 RQLNHSEGCKQRVEQITSQIQEEKLKRRKQRMEFEMQLEELMEKHKSTWEFHN-TESlKKEICNIENAKQQFLSE 152 
NP_001315633  101 RQLEQNHQKEELVKQYSFQIQETKLKHRKIRMKFENQLQQLTEQHKNLSAVFA-PQRlPAEIQSAEYSTEQLLKA 174 
Q9D495        127 RKHSMLQECKERISFLNSQIDKEKAKLRKLRLDFEEHLETLMSQHKDTLEFHK-PEHlTKEMCVLDSSKEQLLKE 200  house mouse
3_pfamImport   79 RKHMLQEFMDQ-IFIRNSQIEESCEQRKWQDLRFKKIHKDIGSRARKL-HFEVlERRlAWEIRALQSSKEQLLTE 151 
5_pfamImport   81 R------------------------------SAAEEQLKDPVARHKALWEFRVlEQRlAREIRALERSQEQLRAQ 125 
ELW62989      820 R------------------------------SDVREELEEPTGLDTDLWEFYMlRQRlAREIRALESSREQLRAE 864 
8_pfamImport   78 S------------------------PQSSQRLDVEEQLEDLMDQHKDLWEFHMlEQRlAQEIGILERSKEQLLAE 128 
Q5D525        125 HLDA---------------------------QQLEERLADLARQHKDLWEFHVlQQRlAQEISTMEHRKDQLLAE 172  house mouse
A8MT33        120 R------------------------------LDVRGQLEDLMGQHKDLWEFHMlEQRlAREIRALERSKEQLLSE 164  human
Q8N0S2        125 RKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHM-PERlAKEICALDSSKEQLLKE 198  human
NP_001137235  125 RKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHM-PERlAKEICALDSSKEQLLKE 198  human
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