8GY7


Conserved Protein Domain Family
MRAP

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pfam15183: MRAP (This model is not part of the current CDD release)
Melanocortin-2 receptor accessory protein family
This family is thought to be involved in cell trafficking. It is required for MC2R expression in certain cell types, suggesting that it is involved in the processing, trafficking or function of MC2R. MRAP may be involved in the intracellular trafficking pathways in adipocyte cells. This family of proteins is found in eukaryotes. Proteins in this family are typically between 47 and 205 amino acids in length.
Statistics
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PSSM-Id: 521695
Aligned: 7 rows
Threshold Bit Score: 128.826
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
8GY7_P        13 MANGTNASAPY--YSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYMSWSASPQMRN---SPKHH 87  human
NP_001129306   1 MANRTDASVPF--TSYEYYLDYIDLIPVDEKKLKANKHSIVIALWLSLATFVVLLFFILLYMSWSGSPQVRH---SPQAY 75 
ELK15947       1 MANRTNASALY--YSFEYYLDYLDLIPVDEKKLRANKHSIVIIFWVSLAVFVVLLFLVLLYMSWSGSPQVRN---NVQHH 75 
Q68UT4         1 MANGTNASAPY--YSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYMSWSGSPQMRN---SPKHH 75  chimpanzee
NP_001092863  13 QQSASNSDYT---WEYEY---Y-EIGPVSFEGLKAHKYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHQDNaesSEKRF 85 
1_pfamImport   1 QSSARRSDYV---WQYEY---YDEEEPVSFEGLKAHRYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHQENqdsGEKRH 74 
XP_004757558  28 MANETNASSAYdgYGYEYYLDYLDLIPVDERKLKANKYFIVITFWVSLASFVMLLFLILLYMSWSGSSQGRN---NTQHH 104
8GY7_P        88 QTCPWSHGLNLHLC 101 human
NP_001129306  76 QVCSWTHGFHLPLC 89 
ELK15947      76 PACPWSFCLDLPLC 89 
Q68UT4        76 QTCPWSHGLNLHLC 89  chimpanzee
NP_001092863  86 RMNSFVSDFGKPLE 99 
1_pfamImport  75 RPGSCLVDIGSPQD 88 
XP_004757558 105 TTCPWSHSLHLPLC 118
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