Conserved Protein Domain Family
CYTL1
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pfam15153: CYTL1 
Cytokine-like protein 1
The function of this family of proteins, CYTL1, has not, as yet, been determined. However it is thought to be a secretory protein expressed in CD34+ haemopoietic cells. This family of proteins is found in eukaryotes. Proteins in this family are typically between 134 and 145 amino acids in length. There are two conserved sequence motifs: PPTCYSR and DDC.
Links
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Statistics
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PSSM-Id: 494871
Aligned: 7 rows
Threshold Bit Score: 182.649
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_006629729   5 VGTFIVLCsliFLA-----NCAPpPTCYSRVLSYSKEIMKFMETLQKSYRtKSCMEALPKMYLDVHNSCIMPKLRDFLyv 79 
XP_003464394   5 TLALLLLL---LLAgp-paSAAP-PTCYSRMLGLSQEITRDFQLLQAVEP-EVCVRYLPRLYLDIHNYCVLAKLRDFV-- 76 
NP_001074575   5 TLPLLLLLvvvVIAwplavQSAP-PTCYSRMLTLSREIMADFQSLQASEPeDSCVRYLPRLYLDIHNYCVLAKLRDFV-- 81 
XP_003441598   5 LAALLCLSslvWLS-----ECTP-PTCYSRALNLSKEIKTLLDKIHTFHRtKTCAEILPTIFLDVHNSCITTKLRDFLyv 78 
XP_002688471   8 LLLLLLLLaglPTT-----RPTP-PTCYSRMLALSREITSDFQSLQATEPsEACVRYLPRLYLDIHNYCVLAKLRDFV-- 79 
1_pfamImport   1 MLPLLLLL----LAvp-paWPAP-PTCYSRMLSLSREVTNDFQRLLAAELqEPCVRHLPRLYLDIHNYCVLAKLRDFV-- 72 
XP_006009617   4 LLKVAVLFtvlAIA-----NAVP-PTCYSRVLTLSEEIMDSVKFLQRFKRtSPCVDVLPKLYLDVHNSCIMSKLRDHLyi 77  coelacanth

XP_006629729  80 lenlTRPECRERPRILGLKRKIRSLYIIINKVCYRDLVFYTDDCDALVTGESTPRQGGD 138
XP_003464394  77 ----ASPQCWRVARVDALKDKVRKLYTIMNSFCRRDLVFLSDDCSALEYPVPVTAGLPD 131
NP_001074575  82 ----ASPQCWKMAEVDTLKDRVRKLYTIMNSFCRRDLVFLSDDCSALEDPIPEATGPPD 136
XP_003441598  79 vlnhPNQYCREKPRMVLLKRKIQNLYSIITRICYRDLVFFTDDCQAIDTGNTRPYYAED 137
XP_002688471  80 ----ASPHCWKLAQVDALKDKVRKLYTIMNSFCRRDLVFLTDDCNALEYPVLVTTVLPD 134
1_pfamImport  73 ----ASPQCWKMAQADALKEKVRKLYTITNVYCRRDLVFLSDDCSALEYPIPVTTILPD 127
XP_006009617  78 lqnlTPPKCRDFPRVTILKNKVRNLYTIMSKVCYRDVVYLSDDCDAMEHPPPTRPSEGR 136 coelacanth
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