7EEB


Conserved Protein Domain Family
CATSPERB_C
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pfam15149: CATSPERB_C (This model is not part of the current CDD release)
CATSPERB, C-terminal domain
This entry includes CATSPERB, an auxiliary subunit of the CatSper complex, a complex involved in sperm cell hyperactivation. This process is needed for sperm motility, which is essential late in the preparation of sperm for fertilisation. This is a multi-domain protein; this entry represents the C-terminal domain which covers the Stem domain and the transmembrane helix, which are involved in the association with the channel domain.
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Statistics
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PSSM-Id: 521677
Aligned: 10 rows
Threshold Bit Score: 406.823
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
7EEB_E        831 CSYLRTMHHTPGRHIPPEDWISGvhKDSQGFNMIKTLPINYRPPSHMGISIPLTDNFYHADPSKPIPRNQFHKSKETGKY 910  house mouse
4_pfamImport    1 CSYLKSMHHIPTRFIPLEDWNRGvhRDSQGFNLIKTLPINYRPPSNMGIAIPLTDNFYHADPSQPIPRNLFYKSKEAGKF 80  
1_pfamImport    1 CSYLKSMRHSPSTLISRDEWLEGvhPFSRDLNMIKTLPVNYRPPSNMGVAIPLTDNFYHADPSKPIPRNLFPKSRESGKF 80  
XP_007473259  834 CSYSKYMNYVPKYEIKGEDWEFGqhKDERGFNMIKVLPINYRPPSNMGIAIPLTNNFYNADPSMPRPRNYHPLSKKSGIY 913 
XP_001641202  851 CPPSKMLHFIYPFTASEDALLAStvKDTLGVVRNKKLPYNYRPPSARGVGIPMTANVYHADPARPQYRDAFVVTRSTYRY 930 
3_pfamImport    1 CSYLRSMHHIPSKLIPLEDWISGihKDDQGFNMIKTLPVNYRPPSKLGIAIPLTDNFYHADPSKPIPRNLFLMSKRTGKF 80  
A2RTF1        831 CSYLRTMHHTPGRHIPPEDWISGvhKDSQGFNMIKTLPINYRPPSHMGISIPLTDNFYHADPSKPIPRNQFHKSKETGKY 910  house mouse
2_pfamImport    1 CSYLRAMRHIPSESIPVEDWIQGvhRDSQGFNMIKTLPVNYRPPSNMGIAIPLTDNFYHADPSQPIPRNLFHKSKVTGKY 80  
XP_007658705  872 CSYGKRMIFASHEKMMHPNSTMG--HESEYDTKMKKLPVNYRPPSNLGIAIPLTDNIYNADPSKGRPRDYFPKSRLTGKY 949 
XP_014341833  860 CPTGKMIYYVSPVAITDSEWLSGnaKDSKGADLLISLPVNYRPPSQRGISIPLTDNIYNADPSKPRLRDYYQTSKKSGKF 939  coelacanth

7EEB_E        911 KQCANVTSRAMCNCSEHQKFSHAVAFSDCKEKVHRFKFPVTQYPVVLEI-FNERDKISAEPPYLVTMTEVNMRKNWQLKH 989  house mouse
4_pfamImport   81 KQCANASNREECNCTNYQKFSYAVAFSDCREKVPRFKFPVSQYPISLEI-YNEDGRVPVKPPYLVTMTEVNKRKNWNLKQ 159 
1_pfamImport   81 KQCANKSNRKQCNCTKDQKLSYAVAFSDCREKVPRFKFPVRQYPVSLDV-YSEDGHIPMETPYLVTVMEVNGRKHWEIKH 159 
XP_007473259  914 KQCLNKTHREDCHCTEEMKKSENIVFSDCKEKVARFLYPVLQYPILLHI-KHDELSIPMDIPYLVTVSEVNNRKNWKLRH 992 
XP_001641202  931 KQCKGKAKRSHCGCTRATKVSSLVQHSDCIEVVYRLLFDEKLTPRFLVL-REGREAETLTSPYY--LEELNNRSDFEIVN 1007
3_pfamImport   81 KQCTNASTREECNCTNNQKFSHAVAFSDCREKVPRFKFPVTQYPISLQI-STKKGNMPVGLPYLVTVTEVNMRENWKLKH 159 
A2RTF1        911 KQCANVTSRAMCNCSEHQKFSHAVAFSDCKEKVHRFKFPVTQYPVVLEI-FNERDKISAEPPYLVTMTEVNMRKNWQLKH 989  house mouse
2_pfamImport   81 KQCANVSTREECNCTDAQKLSYAVAFSDCREKVPRFKFPVTQYPVSLKI-FNESVLIPVKSPYLVTVTEVNLRKNWQLKH 159 
XP_007658705  950 KQCANKTSRAECNCTENQKLSDNVAFSDCKEEVPRQKFPVVKYPIILGI-VSEDGWIPLEPPYLITMTEVNNRETWKLKD 1028
XP_014341833  940 KQCAGKLSREECGCTESMKLSSLAAFSDCRERVLRMTYPVSNMPIKLFLkIGNKPGEPLNSPYFVTVTEVNNRSNWEVTG 1019 coelacanth

7EEB_E        990 NEPE-NVKKMKHYLEPLLKTPVYNPLGLNLTIQGSELFHFKV-SVVPGVSFCELSEEFQIYVDEVPLPFPGHALIAVATS 1067 house mouse
4_pfamImport  160 YLPE-NVKKMKNYLESIVQAPVYNPSGLNLSIKGSELFHFRV-TVIPGVTFCNLVEEFQIYVDEAPLPFPGHTLIAVATA 237 
1_pfamImport  160 TVPE-NVRRLKNYLESILHVPVYNPLGLNLSVKGSELFHFRV-SVVPGVTFCNLVEEFQIYVDEVPLQFPGHTLIAIATA 237 
XP_007473259  993 TVKN-EMKRMKTHVESLFSDLVFNPNGLRLSITGSELFHFRV-KVIPGVTFCNLVDEFQIYVDSAPLPFPGRVLVASLTA 1070
XP_001641202 1008 SSNK-TVLQQAVVMEQAKNSSIY--------FYGSGLFHFRAfAVQENYTFCDLEAEFLVFVDETPLPYPAKDIIRACTA 1078
3_pfamImport  160 STPP-TIRKLQSHLKSHLQVPVYNPIGLNLSIMGSELFHFKV-SVVPGVTFCNLVEEFQIYVDEAPLPFPGHTLIAIAAA 237 
A2RTF1        990 NEPE-NVKKMKHYLEPLLKTPVYNPLGLNLTIQGSELFHFKV-SVVPGVSFCELSEEFQIYVDEVPLPFPGHALIAVATS 1067 house mouse
2_pfamImport  160 SVPV-KIKKLKNYLEPLLHASVYNPLGLNLSIKGSELFHFRV-SVVPGVTFCDLVEEFQIYVDDAPLPFPGHTLIAVAAA 237 
XP_007658705 1029 NESL-GVEKMKKYLKEENKLTVYNPKGLNLSIMGSELFHFRV-TTVPGVTFCPLVVEFQIYVDEVPIAFPGRSLIATTTA 1106
XP_014341833 1020 TNSTpTMLKLRTYLKATLNSTLYNPDGLKITLIGSELFHFRV-SVILGVSMCNLEDEFQIYVDDPPLAFPTSFLIGTGTA 1098 coelacanth

7EEB_E       1068 VVLGVLIFIAFVFQLRNIHP 1087 house mouse
4_pfamImport  238 VILGGLIFIAFMLQLRDIHP 257 
1_pfamImport  238 VVVVCLIYATFMFRIRTVSP 257 
XP_007473259 1071 VVIGGIILMVFMVELFNVNI 1090
XP_001641202 1079 M---GFFTLLYVLYLWNFHF 1095
3_pfamImport  238 IVLGGLIFVVFMFQLRNIHP 257 
A2RTF1       1068 VVLGVLIFIAFVFQLRNIHP 1087 house mouse
2_pfamImport  238 VVLGGLIFTAFMFQLRDIHP 257 
XP_007658705 1107 IFLGGFIFVTFLIKMYNIHA 1126
XP_014341833 1099 VVLGGILFLLFVLYQYDVQV 1118 coelacanth
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