Conserved Protein Domain Family
PIRT

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pfam15099: PIRT (This model is not part of the current CDD release)
Phosphoinositide-interacting protein family
The function of this family, PIRT, is not known, however it is predicted to be a multi-pass membrane protein. This family of proteins is thought to have a role in positively regulating TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2). This family of proteins is found in eukaryotes. Proteins in this family are located in the cell membrane. Proteins in this family are approximately 140 amino acids in length.
Statistics
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PSSM-Id: 521654
Aligned: 2 rows
Threshold Bit Score: 203.393
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_030143467   5 PKSpeeSEKSPQLRELITSDTGSTLCTSSRSESVWTSAPRSKWDIYHKPVVVVSVGAAVFLFGVVITSLSCFLTKNKKVY 84 
XP_046758047  17 PNG---SEKSPPSKELLTSNTASTLCISSRSESVWTNTSRSKWDIYHKPIIVMSVGAAVFLFGTVITTLSCFEFENKAVY 93  chicken
XP_030143467  85 KMSGPAFLSLGLMLLVCGLVWIPIIRKKQKQRQKSQFLQSLKSFFFNR 132
XP_046758047  94 KMCGPAFLSMGLMLLVCGLVWIPIIRKKQKQRQKSQFLQSLKSFFFNR 141 chicken
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