Conserved Protein Domain Family
NRN1
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pfam15056: NRN1 (This model is not part of the current CDD release)
Neuritin protein family
The domain family Neuritin1 (NRN1) is a GPI-anchored protein expressed in post-mitotic-differentiating neurons in the developing nervous system. NRN1 is a glutamate and neurotrophin receptor target encoding a neuronal protein that functions extracellularly to modulate neurite outgrowth (OMIM:607409). This family of proteins is found in eukaryotes. Proteins in this family are typically between and 158 amino acids in length.
Links
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Statistics
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PSSM-Id: 494790
Aligned: 11 rows
Threshold Bit Score: 133.646
Created: 22-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_003226908 106 CDAVFKGFSDCVLKMGQNIALYQQDPDDK------KNLETICRYWDDFHACTLIALTDCqQEGVTDVWEKLKEKSKKLDY 179
1_pfamImport   1 CQNIYQDFSDCILKLGENMANHVYLLLFNskelkeSSFSSCYRYWDEFHTCAMTALWEC-QREAVTIWEMLKKESTKIKF 79 
KAG3280947    31 CDAVFKGFSDCLLKLGDSMANYPQGLDKTr----rTSRPCARKYWEDFHSCTVTALTDC-QEGAKDMWDKLRKESKNLNI 105
NP_001185659  31 CDAVFRGFSDCLLRLGDNMANYPQDLDDK------RNLQTICAYWDDFHACTLTALTDC-QEGATDLWEKLRRESKNLDF 103
XP_015194387  33 CNGIYRGFSECLLRLGDSMSRYVEEelv-----eeQDIDNVCAHWDEFHACGMAVISEC-RVEVQAVWDSLRLQSENLRF 106
XP_009301502  26 CSAVYRGFAECLLTLGDSVSSKTDEn--------pQDINSICKSWDAFQVCVSGVLSGC-RGDAAEIWESLRAESRKTAF 96 
XP_014327598  34 CHSIYKGFARCLMALGDSLTENARKee------etHEIHSICRSWDEFHDCANVAMAGC-PEEAAAVWESLRQESKKMQF 106
XP_015223863  32 CDSIYRGFAECLLRLGDSMTRSVQQgae-----dlQEIDTICRSWDEFHTCANAALAGC-PEEAAAVWESLRQESKKMQF 105
2_pfamImport   1 CENIYKGFSDCVLKLGENMGNYKEEGDET------QQLQIVCGYWEEFHICATTAISEC-QEEASRIWETLKKESKKIKF 73 
XP_016158664  27 CAGAYRGLSDCVLKLGDSMATYEEEEGIEl-----QGLHRVCRYWDEFHTCALTVLWEC-QKEAVAVWEMLRRESQKTKF 100
XP_004069184  80 CENIYKDFSDCVLELGDSMDNYQENVTSE------RGVAAVCSHWEAFHTCALTALSDC-QEEVSSIWETLRQDSRKIRF 152

XP_003226908 180 EGNLFVLCSKTKAA 193
1_pfamImport  80 QGSLFDLCAPSDSQ 93 
KAG3280947   106 QGSLFELCSSGNGA 119
NP_001185659 104 QGSLFELCGGGSGA 117
XP_015194387 107 HGNLYEVCRAREQS 120
XP_009301502  97 AGNLYDICASRTEA 110
XP_014327598 107 SGNLYDMCSNRNSH 120
XP_015223863 106 SGNLYDMCSNRAKP 119
2_pfamImport  74 QGSLFDLCSSNKS- 86 
XP_016158664 101 QGSLFDLCSPSMAQ 114
XP_004069184 153 QGSLFDLCSPSSSS 166
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