Conserved Protein Domain Family
C5orf34-like_N

?
pfam15025: C5orf34-like_N (This model is not part of the current CDD release)
C5orf34-like, N-terminal
This entry represents the N-terminal domain of a family of eukaryotic proteins, including the human uncharacterised protein C5orf34, which has been reported to be correlated with an unfavourable prognosis of patients from a variety of human malignancies. This domain is predicted to show an alpha-beta structure with high structural similarity to a polo box.
Statistics
?
PSSM-Id: 521611
Aligned: 71 rows
Threshold Bit Score: 51.8072
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_031172847   10 MVLFEDESVDVRYGTG---AQLQLSPCGCEFTLLKPaevSghpprspetlRHPPKPAERLRQRTRFTVSSYKEVLVAALA 86 
XP_002505862   73 GIIFDDGAVKCTFSDL---SSIVLDPTGQYFTAHDA-------------------SGETARQLSEFAISRFAPRLRASLE 130
GAX72778        6 IIIEMSGALKANFSDG---TILVLSSKGCNFLVKRE--------------------CHQQRHLTDFALSRHAPALNMVLD 62 
XP_013899500   17 ACVTADGRVKTLWGDN---ALLLLSSGGEAFAHAPP------------------GAPAPTCQISEFALSRAAPLLAQALR 75 
XP_002957261   12 ICVLDDGRAKAIFSDN---TIIVTNSTGSAFIIRTQ-------------------DGHLMRQVSEYALTRHCPLLAAVLE 69 
20_pfamImport   1 ICLLEDARAKANFSDN---TIIVTNSAGSAFSITTP-------------------DGRSVRQMSEYALTRHGPLLAAVLE 58 
KAG2487935     18 VCVLSDSRAKATFSDN---TVVTTNSAGSSFLITTP-------------------DGRSTRQLSEYALARHSPLLAALLE 75 
KAG2448169     14 VCILADCRTKATFNDN---TILSLNSTGSSFLVTTP-------------------DGRCTRQLSEYALARHSPLLAAVLE 71 
RNA07305        7 MVIYLDNSCEAHFCQNetiSRIIISPCGSEFLYSVFd--S----------DNTI--QSSYKYRTAYPLSMFVSKLQNVLA 72 
22_pfamImport   1 MVMFNDDSIEVQFKNH---SFLLLSPCGANYQYHPPtcdG----------LKLVDSINTIRQRSKFATSETKAQVDIAMK 67 
XP_031172847   87 FRN 89 
XP_002505862  131 FRN 133
GAX72778       63 FRN 65 
XP_013899500   76 LRN 78 
XP_002957261   70 FRN 72 
20_pfamImport  59 FRN 61 
KAG2487935     76 FRN 78 
KAG2448169     72 FRN 74 
RNA07305       73 FRN 75 
22_pfamImport  68 ARN 70 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap