pfam14936: p53-inducible11 (This model is not part of the current CDD release)
Tumour protein p53-inducible protein 11
TP53 is a tumour suppressor gene, when switched on it suppresses tumour development by inducing stable growth arrest or cell apoptosis. The tumour protein TP53 inducible protein 11 encoded for by the gene TP53I11, has a protein sequence of 189 amino acids in length and 21 kDa in mass. The role of this protein is thought to negatively regulate cell proliferation in response to stress, and therefore suppress tumour formation.
Jiyao W et al.(2023). "The conserved domain database in 2023.",