Conserved Protein Domain Family
DUF4494
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pfam14902: DUF4494 
Domain of unknown function (DUF4494)
This family of proteins is found in bacteria. Proteins in this family are typically between 154 and 172 amino acids in length. There are two conserved sequence motifs: VDA and EAE. There is a single completely conserved residue E that may be functionally important.
Links
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Statistics
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PSSM-Id: 494655
Aligned: 41 rows
Threshold Bit Score: 118.859
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_015333029   4 WFYGAIAFQQTDdsvavdtqkdgspEAPKMKKVTEAYLFDAVSYTDAEARLYAWIADNT-PDFEITALRPMRL--SDVFQ 80  Fibrella aestua...
5_pfamImport   1 WFEAKVKYMKVN-------------EDGREKKVTEAYLLDAMSYTEAESRIMHEMESVIkGDYYITGLKKSNI--TELVE 65 
WP_014797213   4 WFLCKVSYTKEL-------------EDGTVKRMKDNYLTDATTLTEAEARMHEEVGRSMrGEFSVAAANRMNF--VDVFT 68  Bernardetia lit...
WP_013688708   4 WFTVKVKYTKQL-------------EDGTFKRVSEPYLVAAMTFTDAEARIYEELGSLIrGEFVVTGITRTDF--HDIFH 68  Fluviicola taff...
WP_013455707   4 WFLCKVKYQKED-------------ENGRLKSVTEPYLVDAVSFTEAETRIYEEMGERVrGEFMITGISKSKI--VDVFH 68  Marivirga tract...
WP_008202385   4 WFLCKVKYAKEN-------------EEGLLKNISEQYLVDAVSFTEAEAIIYDRLGEQIrGDFQVTNLSKSNI--VDVFF 68  Algoriphagus ma...
WP_015330915   2 WIQSKIGYEMLV--------------DGEPKQVTESYLHDAVSFADAEQQCFEHLKSRI-TEMEVNALNKLKIgrSDVLF 66  Fibrella aestua...
WP_015812453   4 WYLGKIRYQKED-------------EAGRLKTINETYLVDAVSYTESEARLYKQILTEA-SDFSVTAISRMRL--ADLFS 67  Dyadobacter fer...
WP_015332915   4 WFIGKIRYQQTDdsvavdtqkdgspEAPKLKTINETYLLDAVSYTDAEARLYRVVADNT-PEFEITAIRPMRL--SDVFH 80  Fibrella aestua...
WP_013409777   4 WFQAKIKFVQED-------------EKGVAKNINQVYLFDAVSYTDAEARAYQHLAAEV-PDFQLAGLTKMKI--NEVFF 67  Leadbetterella ...

WP_015333029  81 IdkevgEGIDGETWYRCKTYYMTEDDKG-----RSKKVASAMLINAHNVQQAVERLTEKLSTMLVPVVITDVNTTPILDV 155 Fibrella aestua...
5_pfamImport  66 S-----EDENDDRWYKAKVAIIDADEVSg----KEKSSSQYYLIAAANINKALENLEKALSTFVVPYEIGAIADTQFMDV 136
WP_014797213  69 Y-----ND--AENYYKCKIRYVTIDEAKg----KEREVKNQVLIAANDILDAHTRLTKEFSSMLVPYEIIEMIKTPLVEV 137 Bernardetia lit...
WP_013688708  69 Y-----ED--ADVWYKCKITY-EAGADGgeegaKAKKVSQNFIVTAHSVKDAYERLKESLGGMMIDYVIPSIIISPIVDV 140 Fluviicola taff...
WP_013455707  69 Y-----ED--ADIWHKCKVVYYVAEESG-----KEKKITNQMIVTAKNVKEAYDRIYLSLNNMLVSFQVPEVIESSILEV 136 Marivirga tract...
WP_008202385  69 Y-----ED--ADIWYKCKICYLVTDADSg----KEKKVTQYMIVTAEDVKEAFDRIQESLSNMLVSFRVPDIVESPIVEV 137 Algoriphagus ma...
WP_015330915  67 H-----AHQEGDSFWKVKTKYQT-ETFTg----KAKTVYETFIVPAIDDRQASERVRDSFRDSLTTREIVNVDVTTILAV 136 Fibrella aestua...
WP_015812453  68 Y-----EE--GEQWFKAKVIYFSVDEKSg----KEKKIVNYMLVNAEGIQQALDRINESMRNFLIPYEVTDINLTPILDV 136 Dyadobacter fer...
WP_015332915  81 I-----EG--GDNWYKCKTYYMTEDDKG-----RQKKVVSNMLINGANLREAHQRLADNLSTMLVPVEITDINLTPILEV 148 Fibrella aestua...
WP_013409777  68 E-----EN-SAEIWFKCKVSYIVFDEKSq----KDKKVPYVFLLNAHTIKDAYMILESKL-GTVQDYIITDIGATKILDV 136 Leadbetterella ...

WP_015333029 156 VPY 158 Fibrella aestuarina
5_pfamImport 137 FPY 139
WP_014797213 138 FRY 140 Bernardetia litoralis
WP_013688708 141 FPF 143 Fluviicola taffensis
WP_013455707 137 FNY 139 Marivirga tractuosa
WP_008202385 138 FPY 140 Algoriphagus machipongonensis
WP_015330915 137 Ymp 139 Fibrella aestuarina
WP_015812453 137 FPY 139 Dyadobacter fermentans
WP_015332915 149 VPY 151 Fibrella aestuarina
WP_013409777 137 IPY 139 Leadbetterella byssophila
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