8UYO


Conserved Protein Domain Family
PNMA
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pfam14893: PNMA (This model is not part of the current CDD release)
PNMA
The PNMA family includes paraneoplastic antigens Ma 1, 2 and 3, found in the serum of patients with paraneoplastic neurological disorders. The family also includes modulator of apoptosis 1, which has a role in death receptor-dependent apoptosis.
Links
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Statistics
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PSSM-Id: 521517
Aligned: 15 rows
Threshold Bit Score: 213.735
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8UYO_1       168 FSGSAVPAPEEESFEVWLEQATEIVKEWP-VTEAEKKRWLAESLRGPALDLMHIVQADNPSISVEECLEAFKQVFGSLES 246 human
XP_014584755 161 FSGSVSPGPGEENFEGWLEQVTDMMQIWQ-VPEVEKMRRLLESLRGSALSIMRVLRANNDSMTMEQCLDALKEIFGNKED 239
Q96PV4       162 FSGTASPSPGEETFEDWLEQVTEIMPIWQ-VSEVEKRRRLLESLRGPALSIMRVLQANNDSITVEQCLDALKQIFGDKED 240 human
Q5DTT8       163 FSGSPFPGPGEESFETWLEEVTELMQLWQ-VSEREKKQCLLESLRGSALSIMQALWTSNDSLTVEQCLKALKHIFGNKED 241 house mouse
3_pfamImport   1 FSGREQPGCGEESFESWLDHAKDMLYLWRhTSERERRRRLVESLGGPALDLMCGLLAEHPDTPAQDCLDALEQVFGNNDT 80 
XP_002914729 164 FSGRDIPGPGEETFDPWLEHTNEVIEEWQ-VSDVEKRRRLMESLRGPAADVIRILKTNNPSITTAECLKALEQVFGSVES 242
Q5BJV6       170 FSGRDPPGPGEEEFESWMFHTSQVMKTWQ-VSDVEKRRRLMESLRGPAFEIIRVLKINNPFITVAECLKTLETIFGIIDN 248 Norway rat
XP_004754851 169 FSGSNPPEPGEEEFESWLFHTTEMMKTWR-VSDMEKRRRLLESLRGPAFDVIRVLKTDNPFITVAECLQALEQVFGVIDN 247
NP_001099812 167 FSGNTISIPGLLAFDSWLEHTTEMLQMWQ-VPEVEKRRRLMECLRGPALQVVNVLRANNAAITVKECLEALRQVFGSVEN 245
Q96BY2       168 FSGRESPEPGEEEFGRWMFHTTQMIKAWQ-VPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEVFGVTDN 246 human

8UYO_1       247 RRTAQVRYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRRIADQVRLEQVMAGATLNQMLWCRLRELKDQGPP-PSFL 325 human
XP_014584755 240 WRTSQFKFLQTFQKTGEKISVFLLRLEPLLQRAVQQSPFSMHSTDMIRLKHILARASMTTTLRGKLEILDQRGHP-PTFL 318
Q96PV4       241 FRASQFRFLQTSPKIGEKVSTFLLRLEPLLQKAVHKSPLSVRSTDMIRLKHLLARVAMTPALRGKLELLDQRGCP-PNFL 319 human
Q5DTT8       242 SKVLQFRFLQSSQKPAEKVSDYLLRLEPLLQKAVQQSPLSAHSADSIRLKHVLSQVSMTTGLRGKLSLLDQQGCP-PTFL 320 house mouse
3_pfamImport  81 RVTARLKLLTCSQQPRESLFAYVMRLEGLLHVAMEQGAVHPAMADQMRAGQVLLQARPNATLQDKLRRMWLERQL-PGFL 159
XP_002914729 243 SRDAQVRFLNTYQNPGEKLSAYVIRLEPLLQKVVEKGAIDKDNVNQARLEQVIAGANHSGAIRRQLWLTGAAEGPaPNLF 322
Q5BJV6       249 PRALQVRYLTTYQKSGEKLSAYVLRLEPLLQKLVQKGAIEKEVVNQARLDQVIAGA-IHKSVRRELGL--PEGSPaPGLL 325 Norway rat
XP_004754851 248 PRELQIKYLTTYQKDEEKLSAYVLRLEPLLQKLVERGVIEKDVVNQARLDQILAGA-VCRTLRRKLAL--PQGGPaPGLL 324
NP_001099812 246 RKIAQLKFCKAYQEPGEKVSSFVVRLETLLQKALEKNAISRKNVNQTRLKRILGGAILSAKLREKLKMLKQRRRP-PGFL 324
Q96BY2       247 PRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVIAGA-VHKTIRRELNL--PEDGPaPGFL 323 human

8UYO_1       326 ELM 328 human
XP_014584755 319 ELV 321
Q96PV4       320 ELM 322 human
Q5DTT8       321 ELM 323 house mouse
3_pfamImport 160 GLL 162
XP_002914729 323 QLL 325
Q5BJV6       326 QLL 328 Norway rat
XP_004754851 325 QLL 327
NP_001099812 325 ALV 327
Q96BY2       324 QLL 326 human
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