Conserved Protein Domain Family
LURAP
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pfam14854: LURAP 
Leucine rich adaptor protein
This family of proteins activate the canonical NF-kappa-B pathway, promote proinflammatory cytokine production and promote the antigen presenting and priming functions of dendritic cells.
Links
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Statistics
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PSSM-Id: 494619
Aligned: 5 rows
Threshold Bit Score: 158.842
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
D4A8G3        39 TSGDVLLPGASSTGHGLGDKIMALRMELAYLRAIDVKILQQLVTLNEGIEAVRWLLEERGTLTSHCSSLTSSQYSLTGGS 118 Norway rat
1_pfamImport   1 HSGNCKCCANSADLKRLESKMLFLKQEMANLRAIDVKLMQQLMSINEGIESIRWMIDDKGSVTSHDDSLTGSLYSLSDSQ 80 
Q4SAP6        44 TSSSCKRRSKSADVERLEDKLLFLRQEMALLRAIDVKLMQQLMSINEGIESIRWMMEDKGGVASPGGSLAGSLYSLTDSQ 123 spotted green p...
Q5BJW5        70 PASGSPRRSHPSALERLETKLHILRQEMVNLRATDVRLMRQLLLINESIESIKWMIEEKATVTSRGSSLSGSLCSL-LES 148 Norway rat
2_pfamImport   1 KLSTSESMDRESGKKGLAEKIRDLKLEMAYLRSIDVKILQQLVAVHEGIEAVKWILEDKSNLTSRCSSLTSSQYSL-VES 79 

D4A8G3       119 PERSRRGSWDSLPDTSstDRLDSVSIGSFLDTVApRELDEQ 159 Norway rat
1_pfamImport  81 DGASLRGSFNSLNDGNs-DGLDGLSVGSYLDTLA-EDLPDD 119
Q4SAP6       124 EGSSTRGSLNSLNDCS--DDLDGLSVGSYLDTLA-EDLLGD 161 spotted green pufferfish
Q5BJW5       149 QSTSLRGSYNSLHDGS--DGLDGISVGSYLDTLA-DDVPGH 186 Norway rat
2_pfamImport  80 QDTSWRGSWNSLQDPN--DKLDNISIGSYLDTLA-DEMDEY 117
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