Conserved Protein Domain Family
TrmI-like_N

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pfam14801: TrmI-like_N (This model is not part of the current CDD release)
TrmI-like N-terminal
This is the N-terminal domain of tRNA (adenine(58)-N(1))- methyltransferase TrmI, a subunit of the tRNA methyltransferase complex that is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA. The exact function of the N-terminus is not known but it is necessary for maintaining the overall folding and for full enzymatic activity.
Statistics
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PSSM-Id: 521457
Aligned: 192 rows
Threshold Bit Score: 45.4525
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_242822409  80 GPLAMGELVVFVDAKLRRRLQRLRPGRVFQAPAGgIVRHESVAGLPEGSSV 130 Thermaerobacter marianensis
SNU00692      11 GPLHDGERVQLTDAKGKMHTIQLRAGEHFHTHRG-GIDHDRIIGQPDGSVI 60 
6_pfamImport   1 GPLREGDRVQVRDPKGRFHTITLVAGGRFQTNRG-WLDHDAVIGQPDGQVI 50 
WP_034503228  18 GPLREGERVQIRDPKGRLHQVILVAGGRFQSNRG-FIDHDDLIGRPDGQVI 67  Actinomyces sp. S6-Spd3
WP_009399746  21 GALAHGDRVQVRDPKGRYHQVVLVAGGRFQSNRG-GFDHDDVIGRPDGQVV 70  Pauljensenia hongkongensis
EJZ86149      33 GLLEEGDRVQVRDPKGRFHQVILTHGGKFQSNRG-EFFHDDLIGKPDGQVI 82 
KFI72681      23 GPFRAGEKVQLTDRRGRRYTEQLVRGAASQTDHG-FIRHDDIIGRDPGVVV 72 
WP_188354748   4 GVLQAGEKVQLTDRKGKFITIQLVTGGSTDTQRG-VIAHDDIIGNVEGSVI 53  Galliscardovia ingluviei
WP_094726598  20 GPLAPGEKVQLTDRKGNMLTFQLVEGGVTDTQHG-QIHHDDILGQGEGRVI 69  Alloscardovia macacae
WP_279075003   6 GVLRAGQKVQLTDRKSNMLTFQLVADGVTDTAHG-QIAHNDIIGEAEGRVI 55  Alloscardovia omnicolens
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