8J07,8TEK


Conserved Protein Domain Family
CFAP91
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pfam14738: CFAP91 (This model is not part of the current CDD release)
Cilia- and flagella-associated protein 91
This entry represents a domain found in the CFAP91 protein. CFAP91 (also known as AMY-1-associating protein expressed in testis 1 or AAT-1) is a component of a spoke-associated complex, regulates flagellar dynein activity by mediating regulatory signals between the radial spokes and dynein arms. It binds to AMY1 and may play a role in spermatogenesis.
Links
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Statistics
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PSSM-Id: 521405
Aligned: 45 rows
Threshold Bit Score: 129.615
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8J07_d1              191 TQTDYRDADVQTDPYSAEYVVc--QDSI-PELLTLATLTWGRGlPAGQAEVEMIERAREKRAWEASLP--------ALSD 259  human
XP_001961692         133 TQTLYRESSAQTLPYLPEAFEtedLDQA-LELFTLPSILPGDG-PPGAYEVDVFERANKRRALLMAMRsnik-lrqADAR 209 
XP_002038932         149 TQTLYRESSAQTLAYLPEIYDddeART--LELFTLPSVLPGDK-PPGLYEVEVFERARRRHKFLDALKlqikhqrhHDQK 225 
Q9VJC4               166 TQTLYRESSAQTLAFLPEILNkdkSET--FELYTLAKLLPGDK-PPGLHEVEFLERARRRWKFSKALKdnfkrllcEARE 242  fruit fly
EDW39774             161 TQTLYREASAQTLAYLPETEDkeiDEH--LELFRLASALPGDK-PPGLYEVEVLERSRKRWAFNKALNtnlkrqlqEARE 237 
EDW39777             165 TQTLYRESSAQTVAYLPEIMDkeiDEH--LELFCLPSLLPGDK-PPGLHEVEILERARKRWAFNKAVKtnfmkqlhAARE 241 
WGS:AAQB:GK18223-PB  160 TQTLYRESSAQTVAYLPDVMDk--EIVDgLELFNLSAILPGDK-PPGLYEVEVLERARKRWAFNEALKtnfsrkmqDARK 236 
XP_001989258         176 TQTLYRESSAQTVAYLPDIMDkeqDEH--LELFNLATLLPGDK-PPGLNEVEILERARKRWAFNQALKtsfrrqlhEARE 252 
XP_001961693         164 TQTLYRESSAQTLAYLPEIQEa-eKSQK-LELFSLSQVLPGDK-PPGLQEVEILERSRRRWLFRDALKhnfqslfnEARE 240 
XP_002038930         139 TQTLYRESSAQTMAYLPEIFEpnsVET--LELFSLPSIFPVAN-RPGLHEVEILERARKRWAFSDALKvhfknllqDARK 215 

8J07_d1              260 TSQFEKRRKMMNEMERKEWAFREQEIEKLQEIRLEVLKELLRKREENQNEVNMKHLNARWSKLQEGKEAKMAKIQRTHVS 339  human
XP_001961692         210 KLEFQKYKNLLEAFEWSEWIQREEYIQECQMLRLEIVIKMFDKREKEMHAASKRRIEQACERIEKRRQADLRKNEIEYQR 289 
XP_002038932         226 LDF-NRYKMMAEAFEWEHWMEREERIQECQMMRLEIVIKMFDKREREMHAASKTRIEQGCEKIEKRRKAALRKNEIEYQR 304 
Q9VJC4               243 VSIKTQYKEILEAFEWEQWIQREEDIQQCQMMRLEIVIKMFDKREKEMHNASKARIEKSVQQIEKRRQDGLRKNEIEYQR 322  fruit fly
EDW39774             238 LAMETKYKSILEAFEWESWIEREECIQECQKRRLEIVIKMFDKREKEMHLSSKKRIEMACEGIAERRQAALHKNEIEYQR 317 
EDW39777             242 LTMQTKYKHILEAFEWESWIEREEYIQECQMMRLEIVIKMFDKREKEMHLASKTRIEIACERIEKRRQEGLHKNKMEYLR 321 
WGS:AAQB:GK18223-PB  237 EAMNNKYKSIFEAFEWEHWIQREEYIQECQMMRLEIVIRMFDKREKEMHEASKTRIEMACERIEKKRRIGLQKNEIEYQR 316 
XP_001989258         253 KAIKSKYRPILEAFEWEHWMEREEYIQECQMMRLEIVIRMFDKREKQMHAESKTRIEVACEGIEQKRQRGLAKNEVEYQR 332 
XP_001961693         241 FEIKTKYKPILEAFEWEQWIEREESIQECQMMRLEIVIKMFNKREKEMHASSNARIEQACERIEKRRQAGLRKNEIEYQR 320 
XP_002038930         216 VAIKTELKDILEAIEWEQWIQREEDIQECQMMRLQIVIKMFDKREKEIHAASKTRIETACERIEQRREAGLRKNEIEFQR 295 

8J07_d1              340 TIRK 343  human
XP_001961692         290 GMRR 293 
XP_002038932         305 GMRR 308 
Q9VJC4               323 GMRR 326  fruit fly
EDW39774             318 GKRR 321 
EDW39777             322 G--K 323 
WGS:AAQB:GK18223-PB  317 GMRR 320 
XP_001989258         333 AMRR 336 
XP_001961693         321 GMRR 324 
XP_002038930         296 GMRR 299
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