6M3C,1X7A


Conserved Protein Domain Family
FXa_inhibition

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pfam14670: FXa_inhibition (This model is not part of the current CDD release)
Coagulation Factor Xa inhibitory site
This short domain on coagulation enzyme factor Xa is found to be the target for a potent inhibitor of coagulation, TAK-442.
Statistics
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PSSM-Id: 521352
Aligned: 88 rows
Threshold Bit Score: 25.6777
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6M3C_B          98 CSLDNGGCT----HYCL-EE-VGWRRCSCAPGYKLG-DDLLQC 133  human
20_pfamImport    1 CKENNGGCGppttTRCA-VS-NGTRTCSCFEGYT-S-PTGENC 39  
XP_004990506   472 CVTDNGGCGnastTLCM-KTgPNERECSCRDGFT-S-ETGRDC 511 
21_pfamImport    1 CTNNVKGCDls-sTTCR-KTgPGTAECDCKSGYR-R-RTSTSC 39  
22_pfamImport    1 CDTNNGGCGs--nSQCD-HTgPGTRRCTCDAGFRSTsNDGANC 40  
23_pfamImport    1 CEQTPGPCGd--nSKCS-PTgPGTYTCLCEQGYESDdSAQTNC 40  
24_pfamImport    1 CMENEGICGd--nATCEfAG-PGKYTCLCASGYEHD-SPTDKC 39  
19_pfamImport    1 CEDVPGRCGe--nSLCV-YDgPDKFHCTCVEGYESAnAENTDC 40  
25_pfamImport    1 CSDNPNICGr--nSQCS-MTgPGTYRCTCEDGYSSStADNKNC 40  
EDO49497        99 CGWKNGGCS----QLCL-VTgKNTRRCTCIIGYRLI-GDGRTC 135 
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