Conserved Protein Domain Family
Haem_oxygenas_2
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pfam14518: Haem_oxygenas_2 (This model is not part of the current CDD release)
Iron-containing redox enzyme
The CADD, Chlamydia protein associating with death domains, crystal structure reveals a dimer of seven-helical bundles. Each bundle contains a di-iron centre adjacent to an internal cavity that forms an active site similar to that of methane mono-oxygenase hydrolase.
Links
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Statistics
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PSSM-Id: 494330
Aligned: 109 rows
Threshold Bit Score: 66.6121
Created: 22-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_012733411  37 QNFVIHRFPIKNHWTRNILGIASRIPd---HQLRVELVENVFeEETGHFSHSKRHLETFVDFGKALGVTQRDIDTAPML- 112 Burkholderia gl...
WP_012185650  97 LGYVLEHQHFLRNWVRVLATIVAKTDk---DDVVRYELENMSvEFLGYRNRPS-HYELLIRMGESLGMSRAEILSTPPL- 171 Caldivirga maqu...
Q6KZ95        36 KRFSIEFYHFTREWPQILSTLLVNTPn---EDDARELTTILV-SELGGEDPAKRHELLYRRYLRSINMNPEELVKREKL- 110 Picrophilus tor...
WP_011769356 547 HAFLTQAYHHVKQTVPLLMACGSRLCed-yEWLRYALAQYIE-EEKG-------HQEWILNDITACGFDAEIVRNNEGVg 617 Psychromonas in...
Q5R011        38 QAFLSQAYHHVKHTVPLLMRCGSRLSln-dEWLRKAVIEYIG-EEYG-------HERWILNDLDAAGGDVDMVQNSEPHt 108 Idiomarina loih...
WP_043108585  38 QAFLTQAYHHVKHTVPLLMATGARLPeh-lEWLREAVGEYIE-EEMG-------HQEWILDDLAATGADPEAVRNGEPLp 108 endosymbiont of...
WP_011830251  38 LAFLTQAYHHVRHTVPLLQACRERVGssrpAWLTDALDEYVE-EERG-------HDEWILDDIAACGGDKEAVRHGTPGh 109 Methylibium pet...
EEF24026      38 RAFLTQAYHHVKHTTPLLMACGGRLSge-yEWLRTAIGEYIE-EEMG-------HQEWVLNDIAACGGDKESVRHSTTAa 108
WP_015005628  38 IAFLEQAYHHVKHTVPLLMAAGARIPee-kEWLRNALAEYIE-EELG-------HQEWILNDLAVCGVDKERVRHDAPAf 108 Cycloclasticus ...
WP_012394262  39 IRYLREIYHVVCHTTRIYSLAGARLGne-dRKLRDWFFDESH-EENN-------HDLMAVNDLRAYGEDPERVLAEPPM- 108 Mycobacterium m...

WP_012733411 113 ---PQTQAVIDHnveacnttvhFT---------AGV-ASVLLLMEGQPpvvSAGNQSMLSVMRDv-YRLPPEG---YEFF 175 Burkholderia gl...
WP_012185650 172 ---KATLDSINV----------WRrianer--twvetMAAMHSLELAAdksLRKYGARMHYFNEaiLSSPEYPdavKEFL 236 Caldivirga maqu...
Q6KZ95       111 ---PTTKAWLDG----------MReff---asdYAVaLGSEFGLENMA---IPMWDKLIPGLKImkEKYPNMD---ITYF 168 Picrophilus tor...
WP_011769356 618 kigT-AMELMVA----------YLyhqidrknpLAF-LGMVWVLEGTS---VNVGGKIAELVQHk-LDLPDTA---MSYL 678 Psychromonas in...
Q5R011       109 -----PTQAMVS----------LVynaidnvhpTAF-FGMAHVLEGTS---VKLATAAAHKIQSt-LGLPESA---FSYL 165 Idiomarina loih...
WP_043108585 109 -----ATELMVT----------YAwdtihrrnpVGF-FGMVLVLEGTS---VTLATHAADNIRRa-LGLPPAA---FRYL 165 endosymbiont of...
WP_011830251 110 -----ATEVMVA----------YAydtiargnpLGF-FGMVHVLEGTS---VSLALMAADRIQVn-LRLPDAA---FSYL 166 Methylibium pet...
EEF24026     109 daaCHETEVMVA----------YAydminrvnpLGF-FGMVLVLEGTS---TAVATQAGEKIMQa-LKLPKKA---FSYL 170
WP_015005628 109 -----ETELMVA----------YAydvinrvnpLGF-FGMVHVLEGTS---VTTADRAADGIQEv-LSLPDEA---FSYL 165 Cycloclasticus ...
WP_012394262 109 ---AGAWGIISQ-----------GyylatygnpLGI-LGVASVTEAVG---ATLTGVVARELVEq-YGFEPKQ---TTFL 166 Mycobacterium m...

WP_012733411 176 VHHASaveraggdhtaVSDLeedHAETA-EILLDTYCTT-DELRIQAHRYLDRAIDRRH 232 Burkholderia glumae
WP_012185650 237 REGYE-----------ADEH---HAGEAlELVEKYAGEM--NLIEEVQVTVLESLDALH 279 Caldivirga maquilingensis
Q6KZ95       169 TFHRE-----------IESA---HE----DATANIVGIHtDKEKNDFMEGARRILDLEE 209 Picrophilus torridus
WP_011769356 679 TSHST-----------LDQK---HIKLFaSLMNKITDKN---DQQAIIDGANMVFKLYG 720 Psychromonas ingrahamii
Q5R011       166 LSHGD-----------LDQD---HVQFFeQLMNRVEDAD---AQRAIIQTAKHVYRLYG 207 Idiomarina loihiensis
WP_043108585 166 TSHGS-----------LDEG---HISFYeNLVNRLEDPE---DCRAVIHAARMFYRLYG 207 endosymbiont of unidentified scaly s...
WP_011830251 167 RSHGT-----------LDQE---HTAHFeLLMDRLDDRA---DQDAIVHAARAFYRLYG 208 Methylibium petroleiphilum
EEF24026     171 FSHGS-----------LDLS---HVTFYeSLMNQVTKPE---DQQIIIHAAKRFYRLYG 212
WP_015005628 166 RSHGA-----------LDQD---HVQFFeSLMNKINQPA---EQQLIIRCAKQFYRLYG 207 Cycloclasticus sp. P1
WP_012394262 167 RAHSG-----------FDVK---HIEDVkKAVNNLVQDS---DFDSIVQGRRMTIHFYS 208 Mycobacterium marinum
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