Conserved Protein Domain Family
Prok-E2_E
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pfam14462: Prok-E2_E (This model is not part of the current CDD release)
Prokaryotic E2 family E
A member of the E2/UBC superfamily of proteins found in diverse bacteria. Analysis of the active site residues suggest that members of this family are inactive as they lack the characteristic catalytic residues of the E2 enzymes. They are usually fused to or in the neighborhood of a multi/poly ubiquitin domain protein. Other proteins of the ubiquitin modification pathway such as the E1 and JAB proteins are also found in its gene neighborhood along with a distinct predicted metal-binding protein.
Links
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Statistics
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PSSM-Id: 494285
Aligned: 9 rows
Threshold Bit Score: 170.615
Created: 22-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_009207079   6 DDDYVNLRERGITYEESEP---QRFFIFTHFTLPESLYTVASCDVLVVIPPNYNQDGNDMFWTFPRLYRADGKPIPAvld 82  Sulfuricella de...
WP_011811445 189 DADERYLSSHGVVFETVSDg-aHTGVIFKQLPLPAGKFNHAAADVLVLLPPGYPDVAPDMFYCDPWLTLQSVGRCPT--- 264 Verminephrobact...
WP_011801832 189 EADQRYLDSHGFTVEVVSDg-pHTGVVLKQMQLPQGKFNHPAADVLVILPPGYPDVAPDMFFCNLWLTLVSAGRYPT--- 264 Polaromonas nap...
WP_009206947   5 VRDVKFLSEREFKWEVVPDpqgAVCLLIKEFDVTAGGFTPSMIDLMIRIPPQYPMSPLDMWYCDPPIRLTTTGQFAQ--- 81  Sulfuricella de...
WP_012590964  11 PVDHEFLDEYGLSWETIVDg--SQWVLIHDLPTPHG-YNHTRVTAAIRIETGYPNTELNMVYFFPALARIDGKPIG---- 83  Methylocella si...
Q1QNK3       246 PVDERHLDTMGLKWETVVDg-gRRWLLIEGYPVPEG-YNAAVVTLALEIPGPYPGAQIDMFYVHPALRRLVGEEIP---- 319 Nitrobacter ham...
Q8ZSK7         6 SNDRQYLENRGLPFEEVVDa-sQKGVILREFQLPLGRFDTEQADILILLPSGYPDAPPDMFYLLPWVKLVQGAKYPK--- 81  Nostoc sp. PCC ...
Q6YRV0         7 ESDRQYLANKDYTYEEITEg-sRKGLIFSKFPLPNQKYDVSEVDLLILLPNGYPDIVPDMFYLEPAVKLVQGNRPPR--- 82  Synechocystis s...
WP_015146106 159 SQDREYLKSRSLDFEEIVDg-sKCGVVFPGFPLPTQ-FDANQTDLLLILPSGYPDAPPDMFFLDPWIKLRQGNCFPK--- 233 Pseudanabaena s...

WP_009207079  83 pAGGDNRILNGKEYCRWSRHwqsgPGMWRPGRDDIISIYRRIVWALQ 129 Sulfuricella denitrificans
WP_011811445 265 -CADQAHAFQGHSWQRWSRH----NTAWRPGIDGLHTMLKRIEHAMA 306 Verminephrobacter eiseniae
WP_011801832 265 -CADQPHTFMGHNWQRWSRH----NNSWRPGVDGLHTMIKRIEHALA 306 Polaromonas naphthalenivorans
WP_009206947  82 -ATEVMESHLGRSWQRFSRHl---NGNWQPGVDCLRTFFALIQRELq 124 Sulfuricella denitrificans
WP_012590964  84 -ATEAQQALDGKTYQRWSRHrt-gENPWKIGRDHLGTHVILIEDWLE 128 Methylocella silvestris
Q1QNK3       320 -ATQATETVLGRIFQRWSRHrg-pNSPWSSRLDNVMTHLTLVDGALA 364 Nitrobacter hamburgensis X14
Q8ZSK7        82 -AADQPHQFNGQKWQRWSRH----NNEWRPGTDGIWTMLKRIENALE 123 Nostoc sp. PCC 7120
Q6YRV0        83 -ATEARQQFNGRSWQRWSRH----EREWRRGVDGIWTMLKRVEHALE 124 Synechocystis sp. PCC 6803
WP_015146106 234 -AANQPYAFDGRSWQRWSRH----NREWRPGVDGIWTMLKRVEHALE 275 Pseudanabaena sp. PCC 7367
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