Conserved Protein Domain Family
Prok-E2_B
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pfam14461: Prok-E2_B 
Prokaryotic E2 family B
A member of the E2/UBC superfamily of proteins found in several bacteria. The active site residues are similar to the eukaryotic E2 proteins but lack the conserved asparagine. Members of this family are usually fused to an E1 domain at the C-terminus. The protein is usually in the gene neighborhood of a gene encoding a member of the pol-beta nucleotidyltransferase superfamily. Many of the operons in this family are in ICE-like mobile elements and plasmids.
Links
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Statistics
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PSSM-Id: 433970
Aligned: 5 rows
Threshold Bit Score: 152.311
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9KVG6         12 C-----GFRYTPA-KQMPKGILLDTKSRRKGYYVKEYST---KGGVFVIALVLWNDpHIQLPfAYILQQPEQYKgrLLPH 82  Vibrio cholera...
Q2NBP1          4 L-----ADRWRAI-AATLANKGFTEQQGASPEFRGSINV---HGRAVDIELVIPDSkFVELP-IVRLVDRKQLPagAFGH 73  Erythrobacter ...
WP_013299180   17 Rl---gAYLLSAFdAQPFSASDLQAYNGKKVDRGWR------LPGDPPLHLLLDPE-FPYAPpRIALPDETQRL--LWPH 84  Parvularcula b...
A0AW81         19 S--------WLQDlGIACRIDETKRDDHQTLTMELSVPEtvtGTAPLELTAVFPDF-YPLVPpKVFAVDLG-----MPHH 84  Arthrobacter s...
jgi:Gura_2212  17 LlvksvAELHPKRlAEPWAKDRFVCRSYKLVIEL--------NGVPVDFYFGVKKS-FPLSLpYIFLAQWDSFG--ILPH 85 

Q9KVG6         83 INF-G---FCLCYVTQMEADWNSNDLKSTYQDVD-EQIQLTLDNSVASVEsgtsnDVELEGEFSAYWQSEEELYL 152 Vibrio cholerae O1 ...
Q2NBP1         74 ISRdDiegSVVCFAPATGLPLDFHDPGGSVLRVL-RQTELSLEKSFAGQG-----GAEVAAEYQEYWIEKEPNFR 142 Erythrobacter litor...
WP_013299180   85 VET-A---GLLCVFPT-QTNIDAFEPEKVATALI-TDARDLITRNQSGDL-----DEEFRKEFQSYWTLAIDDKA 148 Parvularcula bermud...
A0AW81         85 WNPfS---NEVCLL---GTPSEEWGTNGSLAQLLkDQLPAALKAGMSGDEhadwnEKPQAEPFGAYYNSYANSAM 153 Arthrobacter sp. FB24
jgi:Gura_2212  86 VET-D---GYICYAQEDGSVLDFDDVAGIAQEAL-SRAIQVVVDGISGKN-----HQDFLDEFGAYWDRLKKVKF 150
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