pfam14411: LHH (This model is not part of the current CDD release)
A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LHH is a predicted nuclease of the HNH/ENDO VII superfamily of the treble clef fold. The name is derived from the conserved motif, LHH. It is found in bacterial polymorphic toxin systems and functions as a toxin module. Like WHH and AHH, LHH nuclease contain 4 conserved histidines of which, the first one is predicted to bind metal-ion and other three ones are involved in activation of water molecule for hydrolysis.
Jiyao W et al.(2023). "The conserved domain database in 2023.",