Conserved Protein Domain Family
Lzipper-MIP1
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pfam14389: Lzipper-MIP1 (This model is not part of the current CDD release)
Leucine-zipper of ternary complex factor MIP1
This leucine-zipper is towards the N-terminus of MIP1 proteins. These proteins, here largely from plants, are subunits of the TORC2 (rictor-mTOR) protein complex controlling cell growth and proliferation. The leucine-zipper is likely to be the region that interacts with plant MADS-box factors,
Links
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Statistics
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PSSM-Id: 521192
Aligned: 57 rows
Threshold Bit Score: 51.414
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_044457944   47 QHNRRRMDLEHEVAELKQQLSNEETVHHILERALhptttAASPssaRSvllNIPAFIPAKAKQLLAELVLVEEEIARLES 126
CBI18365       74 gacPYRFQLEQDVERLQRQLQEEMELHAILENAI-----EKNT----GelsSSSC-LPHNAQVLLANISVLELTVSKLEQ 143
NP_001320120   88 TKLWYKCELEQDIKRLQQQLQEEINLRLALTSAV------EHS---SSpfmDSPCELPDKAQELLDSLAILEITVSKLEQ 158
XP_002516180   90 nMSLYRYQLEEDVKKLQQQLQEEIDLRLALASAV-----EHSN----SsfsSSPYQLPDKAQELLDSIAILEIAVSKLEQ 160
Q5Z663         69 RMRRYRSELEQEVKKLQRQLEEEIDLQLALTDAI-----TNNA----TlilEPSAKLPNKAQELIISIASLENTVSKLEK 139 Japanese rice
XP_006656456   18 ASSSCRSQLEQDVKKLQKALQEETALHSILENAL-----HRAA----LtlaDMSY-LPTNAQELLSNISILEGTISKLED 87 
XP_044960069    9 rRKGFRSHLEQEVLRLQEVLREETALHAILDNAL-----DHAA----VtlaDMSY-LPTHAQELLSSISAMEAAVSKLEE 78 
15_pfamImport   1 FHQLYKFELEHDVKRLKDQLQKETALRTLLLKAS-----DQSH---KIelsHTSS-LPRGVQELLSSIVTMEATVTMLEE 71 
Q8L7U6         40 FHH-YRFELEHDVKRLKNQLQKETAMRALLLKAS-----DQSH---KIelsHASS-LPRSVQELLTNIAAMEATVSKLEQ 109 thale cress
NP_187906      15 esfpYRFQLEEDVKRLQLQLQQEIDLHTFLESVM-----EKDP----WelsYSS-SVPHPAQELLSNIVTLETAVTKLEQ 84  thale cress

XP_044457944  127 QIHTMKGDLI 136
CBI18365      144 EMVSLHFKLS 153
NP_001320120  159 ESVSLRYLLR 168
XP_002516180  161 ESVSLQYELS 170
Q5Z663        140 DLNDLCYQLC 149 Japanese rice
XP_006656456   88 EMVSLHFQLI 97 
XP_044960069   79 EMVALHFQLI 88 
15_pfamImport  72 EIMSLHFLLI 81 
Q8L7U6        110 EIMSLHFLLI 119 thale cress
NP_187906      85 EMMSLNFQLS 94  thale cress
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