7JQ9,7JQ9,2MBB,2MUL,2KHU,2L0F,2KWU


Conserved Protein Domain Family
UBM
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pfam14377: UBM (This model is not part of the current CDD release)
Ubiquitin binding region
This family contains repetitive element (RE) from a subgroup of HECT E3 ubiquitin ligases and the Y-family translesion polymerases, including human HUWE1 and Arabidopsis UPL1. Each of these repetitive elements are approximately 20 amino acids in length and contain two predicted helical segments separated by a Leu-Pro motif. The REs from the Y-family polymerases were shown to bind ubiquitin and were the basis for a novel ubiquitin-binding domain called the ubiquitin-binding motif (UBM).
Links
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Statistics
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PSSM-Id: 521184
Aligned: 170 rows
Threshold Bit Score: 28.6338
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
7JQ9_A       3047 GNPGVTEVSP-EFLAALPPAIQEEVLAQQRAEQQR 3080 human
XP_046441699 3144 PANPNEPVDPaDFLSTLPPALRQSILADMEDSQMA 3178
XP_002430068 2899 STNHNDPFDAaAFFQNLPLSLRQSILADIEESQIS 2933
XP_008200046 2911 QANPNEPVDAgAFFETLQPSLRTMILSDMEDSQMS 2945
XP_009019139 2992 SQNPETPMDPaSFIQSLPSSLRQQVLADMDDSMVA 3026
XP_002111872 2797 APTSEQSFDPaSFVRDLNPSLRRTVLADMDDTHVN 2831
XP_009267625 2683 VGAVGAMGDPsPFFNSIEPSMRQFILMN--GEMLD 2715
XP_006956085 2699 GSQPGNPPDPgSFLTSMDSGLRQFVLMNGD--LYN 2731
7JQ9_A       3086 NASSDTPMDPvTFIQTLPSDLRRSVLEDMEDSVLA 3120 human
XP_026689880 3256 QAAAGENLDPtTFIQTLPPELRQSVLSDMDESLVA 3290 vase tunicate
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