Conserved Protein Domain Family
DUF4407
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pfam14362: DUF4407 (This model is not part of the current CDD release)
Domain of unknown function (DUF4407)
This family of proteins is found in bacteria. Proteins in this family are typically between 366 and 597 amino acids in length. There is a single completely conserved residue R that may be functionally important.
Links
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Statistics
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PSSM-Id: 521175
Aligned: 61 rows
Threshold Bit Score: 135.476
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_014742141        21 DVLSVAP-GSRAKYVALGGVLLSTGGLAAVSAAFAVHMALGAPWL-LASVIGLGWGLVIVNLDRMLLVGMg--------- 89   Modestob...
WP_015747230        15 dprrpndpDNRVRHTATGLLLLAVGAWAFFATTATFYENLQLPLP-GAALVGALVATVVLTVDILITSSPl--------- 84   Nakamure...
WP_008582102        19 QILGGCTeASRKQLKKYSSAILILVILWSFIGYSFAERYVGAPIW-GRILTAFIFVVIIVQIERQIILTV---------- 87   Niabella...
WP_015753220        18 YLLKNSSeASAKSVKKYLSAILIISILWAFIGYSFAKRYLKTDDV-VSIIVALIMVIVVIQIERQIILNI---------- 86   Robigini...
WP_013443873        17 DILKNCSeASYKALKKYASSILILLFIWGATGYTFAQRYLSVHTWwGCALTALIFMIIVIQIERQVILTV---------- 86   Paludiba...
WP_013871617        11 dpahvtvfTDRARYTCAALFMALYYVYATAGCTFFLMIATGGGIF-PGVLVGLLVAAAVVVYDRFLLSQVsvdfsd-lhe 88   Candidat...
CeBiTec:AFR_38710    9 npdsvtThSDRVLYSSIGVFIVLYFAYATVGGAAFVDASANYTHPwYQWLVGPLVATGVVAYDRAVVGRVainyerldsp 88  
WP_015625420        12 npdsVTThSDRVLYASIGAFIMLYFVYATAGGAAFVDASANYSHPwWMWLVGPLVASGVVAYDRAVVGRVainydrlesa 91   Actinopl...
WP_014694582        16 nprsvtThSDRVLYRSIGVFILLYAVYATLGGAAFIDAGSGYRHPwFQWLVGPLVAIGVVAYDRAVVGRVpisfdqldst 95   unclassi...
WP_014447466        16 nprsvtThSDRVLYRSIGVFIILYFGYATAGGAAFIDASTGYAHPwYQWVVGPLVAIGVVAYDRTVVGRVavnyerldsa 95   Actinopl...

WP_014742141        90 --HDASVFRNVAMAVPRIALGVLLGTVISMPLTLQVFNKEIDATIVTLQAEAADRFTAELDADarya-qipdLQQKIAEE 166  Modestob...
WP_015747230        85 --TSDSPWAKLKVVLTRGLISLTIGIVISHTTILFMYRDALEKIVSDKNAAESAQIVETTTQNskwnatisdANSRIAEY 162  Nakamure...
WP_008582102        88 -------GRSKWLSWFRVAIAFIMAILGSSILDQIIFKDDIQKKMIQIVDRQVNEQ----------------LSGRLTII 144  Niabella...
WP_015753220        87 -------SQSIWPKLFRGLIAIVMAIIGSVIIDQIVFKEDVEKIKIAEIQSQVDEV----------------VPARTRII 143  Robigini...
WP_013443873        87 -------GKNKWIVRFRTLLAILMALIGSTILDQIIFKNDVEKVLVDIRADKINEI----------------SGKRQKTM 143  Paludiba...
WP_013871617        89 edARPHGRPRIGSYAIRVVITLLIAVIVTDPLVLKMFDSEITAELGRRHTDRTATLNAVVEQV---------RSAQLAAL 159  Candidat...
CeBiTec:AFR_38710   89 dpEDLLRKPTFGLYAGRLALALLFAVIITEPLMLSRYQGEIDARLNEVHNEQISKVEVSGAIAa--------YDARLRDL 160 
WP_015625420        92 dpDDLLRRPTLGLYLGRVCLALLFAVIITEPLMLARYQGEIDARLNQVHNEQISEIEQGGAIAa--------YDARLAEL 163  Actinopl...
WP_014694582        96 dpEHLLRRPHLGLYLGRIALALLFALLVTEPLMLARYRGEIDARLAETHSAQLGRLDAGGAVAd--------YRARLTEL 167  unclassi...
WP_014447466        96 dpRHLLRPPTPGLYLGRVGLALLFAVVVTEPLMLARYRGEIDARLAEVHSGQISALDANGPAAg--------FTTALAAL 167  Actinopl...

WP_014742141       167 QAVLAgggqtdsnadprvtaaqadrdAKQQAYDAALASYGQLQAKAQCELDGTC----------GSG---DPGEGDAYVS 233  Modestob...
WP_015747230       163 NQQIA---------------------AADQTLADAQARLDDLKKQWSDDEIC------------VNGdyaANGD------ 203  Nakamure...
WP_008582102       145 DKKLG---------------------ELQVEIDSLDKKNLILYEEIS--------------------------------- 170  Niabella...
WP_015753220       144 QQQIF---------------------DLDSLITVKENALATTQQEFAEKPQ----------------------------- 173  Robigini...
WP_013443873       144 QLEIN---------------------KLNMIIDSLDVINSKLNDEVA--------------------------------- 169  Paludiba...
WP_013871617       160 DDEIK---------------------NDQNQLEAASTAVGKAFTAVTDERE-------------GRGatgLAGNGPVFKL 205  Candidat...
CeBiTec:AFR_38710  161 KKQTV---------------------AENRAVQALNTRAAEKRRDARKLYDQAIadsegngvtrRSGcp----dGGYCDT 215 
WP_015625420       164 KKQGA---------------------ADDAAVQALNTRAAEKRADARKLYQQALadsegdgvsrKAGcp----aGGFCDT 218  Actinopl...
WP_014694582       168 RSDTE---------------------NDDAAVRALADRAAGKRRDARDTYRQALadsagsgvthSPGcp----rKGFCDH 222  unclassi...
WP_014447466       168 REDTA---------------------REDAEVRALTGRAEVKRDDARLLYRQALadsagrgvtrSPGcp----pGGYCHH 222  Actinopl...

WP_014742141       234 -------AAAAAAQQATVRDAAKDEldaadaallaarttagadaasngarsvamAQADLATDQAELARLTALRTAEQDAF 306  Modestob...
WP_015747230       204 -------RCTRGETAQTLLEAYENYrdivfppiq-----------tnhdsvvksLTADRDSQNKILNDAIAAKAAEVASA 265  Nakamure...
WP_008582102       171 -------KQPTIKTVSQTITKIQFRqgdgsfttrpqttisttpipnpkvketeiNEQNLEVFRKQKEDYTQKKIKAEASL 243  Niabella...
WP_015753220       174 -------IRSVLVETREELVQEEDSsgqlqdvkiqlkdykthlisnpigaqipvLDEQIQEHRRMRMAKEDEIVNIRAQT 246  Robigini...
WP_013443873       170 -------KRPTIAVTNVTTEKNPVVnqdgtkttntktivstqhvantrieqiksNTATIDKCRSRLDELYNQKINVEVTV 242  Paludiba...
WP_013871617       206 -------LNDNYAKAVARQNEAAET-----------------------------LATAQSNRSANIERINGDASRQTAEN 249  Candidat...
CeBiTec:AFR_38710  216 lvqrsrgLDDQAARLDAQAARLQDT-----------------------------QKAARTARAAEEADLTTKIADQRTVN 266 
WP_015625420       219 lvrrsrgLDTEAARLDRQAAALQQS-----------------------------QGPARTSRQAEQADLIAKISDQRTAN 269  Actinopl...
WP_014694582       223 lvhrsrsLDEQAAALDRQAAGLQRD-----------------------------QRPERAARAAEQSRLTALLDAERTAN 273  unclassi...
WP_014447466       223 lvqrsrrLDDQAAALDRQAAALQRD-----------------------------QSAARVARAAEQSRLTELIRSEHAAN 273  Actinopl...

WP_014742141       307 AAQNSQADGLLARLEAMDRLAEDRP-AAGTAHVMLFLLFLSVELLPVLMKTLlnfGEPNAYEVLEKLRD 374  Modestobacter italicus
WP_015747230       266 TQATSENTGLAAQTTALVTLLKEDP-----FVWIWPAFFIALDLVVALMKAI---LPESDFDRTRRvkr 326  Nakamurella multipa...
WP_008582102       244 RQELKSKQGFLEELNAIIEILRERS-VALFFYSILFFFLMFLELFVVASKTK---DTKSDYDLVVEHQL 308  Niabella soli
WP_015753220       247 EKELSEKTGLLDEITILFKIILSSW-IAGVVWGCIFLFFLSIELFVLISKSF---ESDSDYDRLVRHQK 311  Robiginitalea bifor...
WP_013443873       243 RKELEANAGFLEELKAMIVLISSEA-LAGVFYFLLFTFILALELLVVVSKTK---DVTCDYDLVVEHQL 307  Paludibacter propio...
WP_013871617       250 NDSAPPPAGVLDHQDALLAVLRHNL-HALLVCVMISLLLIALDLAVLFIKLA---GRNSAYEISVAAAS 314  Candidatus Protofra...
CeBiTec:AFR_38710  267 AESIRADAGFGARTKAMWYLVNSDFwGIGVFYLGVALLLVALDCAAVGLKFV---SHGNAYERTEAREa 332 
WP_015625420       270 AAAIRADSGFGARTKAMWYLVSTDIwGIGVFYIGIALLLVALDCAAVGLKIV---SHGNAYERTEAria 335  Actinoplanes sp. N9...
WP_014694582       274 ADAVRGDAGFGARTAAMWHLVRADFwGVGVYYLGIALLMVALDCAAIGLKFA---SRGNAYERNEARag 339  unclassified Actino...
WP_014447466       274 TAVVRGDSGFGARTAAMWHLITADFwGIGVFYFGIALLLVALDCAAIALKFV---SRGNAYERAEARAa 339  Actinoplanes missou...
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