WP_020435746 14 IIFICEILLFVIG-SVLFLVsr---veNLFNLGL--VAIMILFCMNILF-SIKNFKEN--FLYFFMQLTLFTFQISRPFI 84 Mediterraneibacter P39854 10 IINFVTVLFSIFT-FIGYLN-------NLIGFRV--VTISLCITIAMTV-YLLYKKRK--GFLLVYLIYLFLTNFGVFVT 76 Staphylococcus ... Q4JZ50 17 YLFFWLVVSFGYF-FMMPTFted--leGVVSASL--VQLLLFIIGYVYV-SYLNRSFI--SLYSIFMIVFYLFQNGQVLL 88 Streptococcus p... WP_009553893 12 IEIVSIIVTIILL-TSDIGSk-----nPFVFYSL--YGFVIIALNLCII-ISTQKKVI--TGTTIIYSCFCLFQFGLPIV 80 Ligilactobacill... CDB88733 10 YIFIQIVFLLMSV-ISFVLIe------SSIEFTFvsFIALIYFLCTICSlVCYQKKIF--TAINCFYCVYVLFQIGVPLL 80 WP_015865275 7 FVIHILIVIPLIL-LSYAIYeswfitsSSFVSLL--FLALCIWLL-ITS-KIERTSYF--NPYTLFLVAAILFNGGQVLL 79 Geobacillus sp.... WP_007723462 8 SMVIIMLFVMMGI-IIAILS-------QNYQILA--FILLADFLITLLM-FVKESQKK--IIPIMYLISIFTFIFYLPFK 74 Carnobacterium ... WP_005819088 20 YLNFALSILLFIVnLISGAT-------INYLFFS--YYLLFSFLYITVV-SLKVFSLA--SAFNLFLFGYFMFQISALFV 87 Bacteroides WP_022400687 15 ILIVSIFFALFVF-FARYVI-------ESIPCLQ--YALILFIVYILVS-FLRFVKVV--SCIMIFIYGFILFLCSRVFL 81 Bacteroides 2_pfamImport 1 LIVLFFILIFLQF-ILWVQSp-----sEVIVSFLk-YYSCSIYLFCIVL--LLVVKDVdsLLYTFYVLAFGVFIMSRVFL 71
WP_020435746 85 GMC------KGRKWWEE---SFQKEENIWFALTLIVITETALYIGANIIKFF-HIKIRENNtrssDSIFCKAE-F-V--- 149 Mediterraneibacter P39854 77 NIFl-----ANPLVEYHgdlSWYYINTSNLFSIATFAILTFTILSNFISVFS-KINPSRKF----DIKSKGNN-L-F--- 141 Staphylococcus ... Q4JZ50 89 YSL------GVEYDYFYv-lRYDE--TI--VLQSVIFSTQCLIAAFMAGVF--STKKEVSK----PLYSYMDQ-LeR--- 147 Streptococcus p... WP_009553893 81 ATL------DKNYSSYYl--SILPNEIKVLGAQFTILCIQFFTLGLLVFLNQ-SKDNLKIS----ISYLSDDK-L-I--- 142 Ligilactobacill... CDB88733 81 YAV------VPEYSNPYm--SFFSEDILVNAIEYTLLSLEIFGLTIFIFLRS-G-KRYYSS----RVVFTKKK-A-V--- 141 WP_015865275 80 YAL-------GLNDFILg-gKFQQ-ETINQTIFLVMVGLSFFHLGGLLSEHH-YNKTDKIV----NQKE-KEK-F-S--- 139 Geobacillus sp.... WP_007723462 75 NLI------EQNn-------PMYNEKISFITLIILIIAFNGMKIGLLLGDFK-KKH--AEN----QDLK-----K-K--- 125 Carnobacterium ... WP_005819088 88 SLDt----lL-ERKLMDn-lFLFSEEQINNTLCANSVILNAMFLGCLMS-----IIYLPIK----TNINKANLiY-S--- 148 Bacteroides WP_022400687 82 SIFds--siLFESDKYVf-yTFAD-TTVLEVLLILSVSFVSVIIGYLSSYAKsDFKAKDYT----QFTSQASS-Y-Vytd 151 Bacteroides 2_pfamImport 72 DALgfedayFYVSTWANd-wSYFSLSIQFEMLNSIIFYLLFSFVGFLSSCLF--VDRYNYK----TCVK-NDS-L-I--- 138
WP_020435746 150 SNLRKV-SMI--VFYVTMLFYLIEq-fE-PLIKigtGNYLDYYTNYSs-SLPGFFhtLASFARYS-ICVFLATLPEKKKt 222 Mediterraneibacter P39854 142 YYTGIL-FII--GFTIQFLFYIIT---G-RLAI---NTYGDYVSSIQ--ELPMYT--YGIFFFSI-GIAFAFSNVKKTH- 205 Staphylococcus ... Q4JZ50 148 EKLITT-GKL--FWGAFAIFALPFm-mM-KLVItstSGYFAMIRF-Vg-SLPTITvlFEKMFIASsVFLIVYLKSEETWs 220 Streptococcus p... WP_009553893 143 IRAAKW-LAI--LSGLIVIPLYLIt-vE-KTIV---NGYSQQLRATV--SSNGLFn-IATALFMP-ACLLIYCYESKRKh 210 Ligilactobacill... CDB88733 142 NDERYV-YTIakALFICTGMVTVPl-yTvVAYLtlkTGFSQVTRSLV--AANGLFnlARALFIPA-FFLLIIYGEDKKf- 215 WP_015865275 140 DFELRVmGWL--LLSISIIPTFILl-kN-SIEAvqqGGYFSLYQQEKv-TSFKAAssVLSDFLIP-GTLFLLGGSNLKNk 213 Geobacillus sp.... WP_007723462 126 QNLSIA-ALL--LVCMTA-PAMIYrvyK-DTLIvstQGYASLYQSVDt-Q---LFerIANFNTAY-IYIFLATLPSKKLl 195 Carnobacterium ... WP_005819088 149 ERLQNW-GYL--LFWVALPFTLLKf-yL-EIKLvltEGYYAYYTSSL--SIPFLIsiSRFIFEIG-FFLFLTSLPPKKKf 220 Bacteroides WP_022400687 152 KQLQKI-LYY--LILLSAPGVLYKg-mH-DLMLikqYGYLIMFMEMP--PAPLFAraSWGFFNIV-FPMLLMFVPSRKQf 223 Bacteroides 2_pfamImport 139 FEIRRL-GFF--LFISFCVPYLLYl-yQ-AVKFvveNGYLAVYLNESstTVDNPIlrISDDLCVAgIYLYLSTFPIGKKy 213
WP_020435746 223 FIPL----SLYVLSTIP-SLLIGVRNPAMLSLLFVLSYYLLRDFlvd-dkkWIGkieKGLLAICTPALIIFMGVYAYIRS 296 Mediterraneibacter P39854 206 IKYL----VIILTPQVLfFLITGNRGEVFYPILSALGVLIVRNY-------KIK---WWMIITIVFTLFFVIPFIKVFRN 271 Staphylococcus ... Q4JZ50 221 KFLK----VVILGWSIM-AALTGDRTVGLAGIVTLALIQTLign----rkkKIKfsqYALLVGAAVVVMYLMSFAFQFRM 291 Streptococcus p... WP_009553893 211 TFLN----IIYITSCIL-SLIIGDRTSGIGWIV-AFVFYRYSERsknmkknSISr--PLIIGIIFCLIIYLSFYIGYARV 282 Ligilactobacill... CDB88733 216 TKFS----KLVFFYMCVaSLLSGIRTDGILWLLTYLYTSvkkg-----nkkKLNikyLVLLVG---IVMV-AIYVGQSRV 282 WP_015865275 214 KIPLiisfILIIIYTFI-QFMLGSRSSAIMPLIAYLWLFDMKIk-------KIPr--LPLLSAGAIILFIIFPFIGFIRN 283 Geobacillus sp.... WP_007723462 196 RKSY----IIIIPLLLI-DLLTGRRGIAIVNIMVLITYEILRLVisnrnlnKLNfkyLFPISLITIIVLFSANIVSQIRL 270 Carnobacterium ... WP_005819088 221 LTVS----KVYILVMCL-FFLIGVRNRVILSFLFVLWFYY-RFYskk--spKILf--LLIISISSVALLLLVQLV---RQ 287 Bacteroides WP_022400687 224 KYYC----VLFFLVSSV-SFLKGSRSTLLAPIVYFIWFYYSFYSt-----kKISv-kNIACFILFVA--FVAQGILFLRD 290 Bacteroides 2_pfamImport 214 ILVS----CFYIFTLLI-LLGTGGRSATFTQVLAFLVYLGIRGIrvn--wrWMLr-----FVLIGFSLIYVAQLVNDFRD 281
WP_020435746 297 G------LKIVTGNFLTLIADFFYGQ----------GVTFNVTAIAYGYREGIRLSPHlNFTFGDIIDYIYRGSigqkIF 360 Mediterraneibacter P39854 272 M------DSSSIEKVDINWFSSLVEI----------GYTLRPLGYVTRWIDGGESIVY-GKSYLAPIQNIFSYI----IP 330 Staphylococcus ... Q4JZ50 292 Q------QDSKVSGLQTAVVEMIGTL----------GFSFFPLVLTIRIVPT----SI-NFFRGKSYia-------aiIT 343 Streptococcus p... WP_009553893 283 N------SEISSLSPIKVLESFVAEM----------GFNFTTICFVMMYVPGITP-----YKLGKT--YIEALIlm-iPK 338 Ligilactobacill... CDB88733 283 G------ST-IGSSVGDVLVKVVEEM----------GFNFTTICFVMMYIPSSTKFQI-GGTYLKSILAMYPNSl--dFL 342 WP_015865275 284 S------TE---LNLLDAFREFFMVQnpaiailnemGGSMSTVAYTIELIPNIK-----NFEFGMSYIYGLSTIlp-nIF 348 Geobacillus sp.... WP_007723462 271 D------EQ---IKIESIFSSFFNQQ----------SQTYEMIESSIYYAPELKMISN-NYSLQALYNGVK--Plg-vAM 327 Carnobacterium ... WP_005819088 288 A------GVFLLSDDRSIFSYFFYAQ----------STNFYILPLLQYYDL---HTEV-PFVFa-------------pFF 334 Bacteroides WP_022400687 291 K------DASFNLSISQMLFALFYSQ----------GATYVLLGNYLDYSSDFANS-----TRYSILFSLCTTFl--wFF 347 Bacteroides 2_pfamImport 282 SgfkdldQKKDDVVFTQLIQSFFWQQ----------GTSIQTIGRTIQYVDEVANG-W-LYFVGPITNSFRENRlm-eYL 348
WP_020435746 361 HTEGlt-saNSEFNALHSNNLShils--ylsMkedylngR--GRGSNYLVETWFDFGYVGAF---IFSIILGII--LLYM 430 Mediterraneibacter P39854 331 GLQP-----VNYEMVGYGFRYR---------L-------P--GMGFNVIAEAYYNGAIVGVL---IVMVLLVLL--LWKF 382 Staphylococcus ... Q4JZ50 344 GLIP-----SNFDFLHLTNTLSewnayptelLdtiyhygF--GLDYSLIAEAYINFGSYGWIaifFLCSLIAYF--VRDV 414 Streptococcus p... WP_009553893 339 SIDPtgtirNMVE------NLPhewl--yslIhitynggLdfGVGFSPIGESFLNFGWLGVI---IMFVLGSVV--GRFF 405 Ligilactobacill... CDB88733 343 GIFSn------iENTIGCQWLNdqnhmr-----fgslldF--GSGFSAIGESYMNFGWGGVL---VSCVIAIIVtsLYVD 406 WP_015865275 349 GGIHp----------AATKKLAdwlv--stiDpsfasigG--GYGYSFIAEAYANFGWLGSP---LALLIIGYLy-RSFI 410 Geobacillus sp.... WP_007723462 328 Nwi----lpENGQEEFFQSNLGnalt--yirDpiyyrlgG--RFGTSYIAELFLDFSYLGVF---IFNLILGFI--LSSI 394 Carnobacterium ... WP_005819088 335 NLDTs-----yYDPNGINNLLGnaia--friSpdefregH--GLGSSFIAELY-DLGIVFMS---ILSIGLGFV--MGWF 399 Bacteroides WP_022400687 348 --NPlyrkgQSEELVQHTLSLDdqlm--yavNpelylsgV--GYGSSYIAELYQLGGVLALI---IGSYLIGRI--IKWY 416 Bacteroides 2_pfamImport 349 GL-Gip-ngQTLGTVREGYSWAdwls--ykvSpryylngH--GMGSSAIAESYLLGNMFGVM---IVGYMCTFI--IMRF 417
WP_020435746 431 VY--GfgKRALLSTIILVSLQNIFFIPRAEATGWLTFIVYiqfWLCIAVCYGGTLFCYKTK 489 Mediterraneibacter P39854 383 TN--F--KSFEMLSMGTAIVSVLINNIRNAFSFVPAYILI---IIVIVIILLFIDSYLKKE 436 Staphylococcus aureus Q4JZ50 415 DF--KrkDNLFSQYASLILLYSWFTLPRRKS-YFIFNNFFwyvLFFGLALILVSRSI-KQR 471 Streptococcus pneumoniae WP_009553893 406 GKsdWtkLNNFEKYTYVVLLAGLLTFPRRTTYEFL-KVYEysiIFILLYLWMFCSLFKKLH 465 Ligilactobacillus saerimneri CDB88733 407 GK--NavSKWDRFVETVLFL-ALLTFPRRAFNEFVSNIEYsifIIGLILIVMYRKRFAGKN 464 WP_015865275 411 LKa-QisGETAKLVMVSSFLAYFFFFARGESISQFRPLIWy-sIIPYLGLYLIKDICMMYN 469 Geobacillus sp. WCH70 WP_007723462 395 SK--SnfLNWITFSFVLFLVKTFYFLPRESTFNAINQILSvtnILAMLTVWILSLV-LKQK 452 Carnobacterium sp. AT7 WP_005819088 400 ER--NvkNNRALLAISFYAITNCIYISRSSL---FRNVYMfplLIILVFIALKIRYPFKMK 455 Bacteroides WP_022400687 417 ER--NynKSYTYVYFSWFIIPHLIWTSRGSYFP--SPFLImigVLFYVTLRAVVVTWNKRK 473 Bacteroides 2_pfamImport 418 AG--RckKKYSYMYILFYVLPVFFMSPRAEPLSVITALYR---PFCVLFCVQLI-YWFKRK 472
Jiyao W et al.(2023). "The conserved domain database in 2023.",