2L7K


Conserved Protein Domain Family
TTRAP

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pfam14203: TTRAP (This model is not part of the current CDD release)
Putative tranposon-transfer assisting protein
TTRAP is a family of small bacterial proteins largely from Clostrium difficile. From comparative and other structural studies of the Structure 2L7K, UniProtKB:Q18AW3, it has been suggested that this family is required for interacting with other proteins in order to facilitate the transfer of the transposon CTn4 between different bacterial species. Structure 2L7K comprises an alpha-helical fold of four alpha-helices leading to the production of two clefts, the larger of which displays two highly conserved residues in close proximity, Glu-8 and Lys-48. The gene concerned is part of an operon within transposon CTn4, and is expressed alongside a putative DNA primase, a DNA topoisomerase and conjugal transfer proteins.
Statistics
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PSSM-Id: 494063
Aligned: 17 rows
Threshold Bit Score: 62.2667
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2L7K_A        4 LTIEETNLLSIYNEG-------GKRGLMENINAA-LPFM-DEDMRELAKRTLAKIAPLTENEYAEL 60  Clostridioides difficile 630
2_pfamImport  1 FTVEEINLMCCFNTS-------SRKRLIDDMKSVtLNDM-DGEIAELMYKTVRKLEAMTDAEFEEL 58 
CDC76558      3 FTVEETNLMCCFDTS-------SRSKLISEMKNLpINDL-DNEMAELLYKTVQKLESMTDAEFDEY 60 
5_pfamImport  1 FSQDEINLMCIYDTS-------DKTELLKELRFS-VPYIeDTELKEITETVIDKLERMTNDEFSKL 58 
CDB30807      6 FTVEETNLIAIYYSS-------SRSELLERLRAA-QLLL---DLEPVRQRCLRKVEALTDAEFASL 60 
WP_015573968  4 FTVEEMNLLSIYHEG-------SREQLRENMNAA-LPYM-DADMRELAKRTLSKVDALTETEYAEL 60  Lachnospirales
1_pfamImport  1 LTVEEMNLLSIYHEG-------SKAQLMENMTAA-LPFM-DEDMRPFAERTLQKISPLTENEYAEL 57 
WP_002569181  4 LTVEETNLLSIYNEG-------GKRALIENVNAA-LPYM-DADMRELAKRTLSKVDALTEAEFAEL 60  eubacteria
WP_002584960  5 FTIEEENIVAIYAED-------SRETTLENILAA-MPYM-DEDMRQLAAAAVNKLQAMTDSEFSER 61  Terrabacteria group
WP_014081125  5 FTVEESNLISIFMEEgidsdvgGRKNVINGINKT-LKHLeDDEMVELSLCVLAKLKELTDHEFMKM 69  Clostridia
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