Conserved Protein Domain Family
DndB
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pfam14072: DndB 
DNA-sulfur modification-associated
This is family of bacterial proteins likely to be necessary for binding to DNA and recognising the modification sites. Members are found in bacteria, archaea and on viral plasmids, and are typically between 354 and 474 amino acids in length. There is a conserved DGQHR sequence motif.
Links
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Statistics
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PSSM-Id: 493943
Aligned: 35 rows
Threshold Bit Score: 222.897
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_015810476  21 IKTFVGYNTGFRTLTLNMSLYEVNE-----MTEVANEq--------sLNTIevAQR----------------KLDISHA- 70  Dyadobacter fer...
WP_015211591   8 vPVQRGLQSEHQSYVGSLFFGDVAR-----LLNDGHLyvp-----ndPELPdfAQR----------------KLNPTRV- 60  Allocoleopsis f...
WP_015172827   8 VPVHRGLLSEHQSYVASLLFGDIAR-----LLDVGCLyvp-----ndPELPdfAQR----------------KPNPVRV- 60  Geitlerinema sp...
WP_012085859   9 LPALQIRQGERFIYCFAVDGKVLPS-----FTAVSRVhrs-----naALHG--YQR----------------PEVLSHI- 59  Kineococcus rad...
WP_011838007   4 yvfRNVSQIGEKEYQTVIDGQELAEmwrdgIITYNPE----------------IQRgtkvkrgkdnsevevaVYNKANV- 66  Acetivibrio the...
WP_013174404   4 IPALRGEMGGIQYYLTVWGLGEAAR-----NITYSEElekrqeaeipADLR--AQR----------------KINWPRVr 60  Syntrophothermu...
WP_015188357  31 YPGLIFRQGKRKMVQINVPARDLPI-----LLQAMPStd------ndPDSG--KNR----------------PEVKGHA- 80  Gloeocapsa sp. ...
WP_015130698  37 YPGLIFKQGKRTMLQINVPASDFSG-----LLQAKPStg------ndPDSG--KNR----------------PEVKGHA- 86  Calothrix sp. P...
WP_015151421  32 YPGLIFRQGKRQMVQINVPADDLPT-----LLQAKPSsd------ndPDSG--KNR----------------PEVKGHA- 81  Oscillatoria ac...
WP_015956778  32 yigliFEQGKRKMIQINVPAHDLPT-----LLQAKPStn------ndPDSG--KNR----------------PVIKGHA- 81  Gloeothece citr...

WP_015810476  71 SSIAKYILKGllaaisnsprlngsssfariskaMGEqpyIAIPPLVASLrntgfGgSNLQVLPLKtiGS---EEVACFKI 147 Dyadobacter fer...
WP_015211591  61 KAIAQYILDT-----------------------YQEg-tTFFPPICINV------------------QPlptYKDGSIFL 98  Allocoleopsis f...
WP_015172827  61 KTIAQYILET-----------------------YEDg-sTFFPAICLNV------------------QPrpiYRDGSIVL 98  Geitlerinema sp...
WP_012085859  60 KAIRRYL-ES-----------------------SDA---MLPNAIVLAF-----N-ESVRFQPSRrkNIvdySTMGELII 106 Kineococcus rad...
WP_011838007  67 KKIYTSMLSG-----------------------Q-----YFTDMITLNVledgnEkVEL-------------DDEGNLAV 105 Acetivibrio the...
WP_013174404  61 REVVPYLLQV-----------------------PD----HFFSSLTVEVvypahAkSEITFEPVN-------GEWGYVIL 106 Syntrophothermu...
WP_015188357  81 EEIKTYVVER-----------------------AKAnrpWVLGTITANV-----DeHNITVHELG-------RGLCIVVI 125 Gloeocapsa sp. ...
WP_015130698  87 DEIKKYIVDR-----------------------SRKekpWIVGTLTANL-----ApKDITILELG-------RGICLVVI 131 Calothrix sp. P...
WP_015151421  82 EEIKEYILKR-----------------------ASNgkpWILGTLTANV-----DpSKIELIELG-------RGICLVVI 126 Oscillatoria ac...
WP_015956778  82 EEVKQYILKR-----------------------AKQnkpWILGTLTANI-----DpKDLTLIELG-------RGICLVII 126 Gloeothece citr...

WP_015810476 148 FLSQsDTLw------IVDGQHRRKAIElvsDFIRhvl-tyhKYPargpilLYdggkeqigGDELFvwqvclekmkecTVA 220 Dyadobacter fer...
WP_015211591  99 PYHAvTLR-------LTDGQHRCFGIR---QALKdiqdkqlEYQ------VL--------CQLEL------------GVL 142 Allocoleopsis f...
WP_015172827  99 PYHSvSLR-------LTDGQHRCFGIR---QALKnveddpiKEA------AL--------AQLEL------------GAL 142 Geitlerinema sp...
WP_012085859 107 PIDE-TIDeadkaawLVDGQQRSAAIR---DA------------------NV--------DEFPV------------AAV 144 Kineococcus rad...
WP_011838007 106 DG---EIN-------IADGQHRIRALS---MILE-------GNEkgdtffDL--------TELKF------------PVK 145 Acetivibrio the...
WP_013174404 107 DGTE-ELR-------TLDGQHRLVAIK---EALK-------ESP------GL--------AAEKI------------SVI 142 Syntrophothermu...
WP_015188357 126 PNKV-KLD-------ITDGQHRKSAIQ---ELVLg-----nESH------LI--------SDDDF------------PIT 163 Gloeocapsa sp. ...
WP_015130698 132 RRGV-KLD-------ITDGQHRKRAIH---ELIEs-----pESH------LI--------SDDDF------------AIT 169 Calothrix sp. P...
WP_015151421 127 PRGV-KLD-------ITDGQHRKSAIQ---DLIIg-----kSGE------VI--------GDNDF------------PIT 164 Oscillatoria ac...
WP_015956778 127 DRGV-KLD-------ITDGQHRKQAIH---ELIEs-----pDAK------LI--------GDNDF------------PIT 164 Gloeothece citr...

WP_015810476 221 IEVhlGLDVEKERQLFHDLN-----------------------NLGKRVDRGMAL-------QYDGSNPVNTYIKDHLFA 270 Dyadobacter fer...
WP_015211591 143 LYA--ALSLEEERQAFRDQN-----------------------LLVQRPSVSLSH-------TFDRRSPVVLIAKDLIKR 190 Allocoleopsis f...
WP_015172827 143 IYA--GLPLEQERQAFRDQN-----------------------LLVQRPSVSLAH-------TFDQRSPLVLIAKKLLER 190 Geitlerinema sp...
WP_012085859 145 GFI--THGEEEQRSQFILVNnakplpkglihellpdtvghlpaKYAKRQLPALLMsrlnnedLFSYNDDDSPFQGRIATP 222 Kineococcus rad...
WP_011838007 146 VT---HYNVQTAQQQFHQFS------------------------LGLKISSSRAE-------YFNQTGLANIIVRELMKN 191 Acetivibrio the...
WP_013174404 143 LIP--HRGLKKSQQLFSDLN-----------------------RNAKPTTKTLNI-------LFEWRGLFEQAAKEAMNR 190 Syntrophothermu...
WP_015188357 164 LIL--EADKRQCQIDFKDMA------------------------QTRPLDKSLLL-------SFGEYSGRVGITKELINR 210 Gloeocapsa sp. ...
WP_015130698 170 LVL--EGDFQQCQADFRDMA------------------------QTKQLDKSLLL-------SFGEFSGRVGITKELIKR 216 Calothrix sp. P...
WP_015151421 165 IVL--EPDFNQCQSDFRDMA------------------------QTKQLDKSLLL-------SFGEFEGRVGITKRVIEE 211 Oscillatoria ac...
WP_015956778 165 LVL--EADFNQCQTDFRDMA------------------------QTKNLDKSLLL-------SFGEFEGKVGITKNLIEK 211 Gloeothece citr...

WP_015810476 271 T----IFpesGIQEITERQRKDGIESGF-THQEVVSINALLFLNktsiqsATPSQVDAKIELAN--------RFWKTVAE 337 Dyadobacter fer...
WP_015211591 191 Vp--qFR---NNVEMVENSMGKHNPKLM-TFSTLVTATHHMFPNl-----KSKKDLEPRIDWAA--------TFWATTAS 251 Allocoleopsis f...
WP_015172827 191 Vp--qFH---NNVEMVENGLGKHNPKLM-TFSTLVTATQHMFPNl-----KSKKDLEARADWAM--------TFWAAVGC 251 Geitlerinema sp...
WP_012085859 223 TapdgYIkdnSVLKMIESSLNEGALYQYr--------------------nPSDHSGDADAMLLHl------kIFWSLVRA 276 Kineococcus rad...
WP_011838007 192 Sd---LA---GRVEVVRNSISKNDERHIvTFATLVNAIEIVYKDl----eTRVQAMELSKYLAE---------FFNELIN 252 Acetivibrio the...
WP_013174404 191 Ss--lLA---NRVELEHNSLAQKSKKII-TLGVLYEMSKEILKDrn--gyYDSEMADIPPELVSraagelvqVFDEVLLP 262 Syntrophothermu...
WP_015188357 211 Vs--mFQ---DKTEKIKSTPATKNRLIY-TTNYIARFVSCVFANd-----PADELKNYEVEAAS-----------GSLAE 268 Gloeocapsa sp. ...
WP_015130698 217 Vp--mFQ---GKTEKIKSSPATKQKLIY-TTNFIARFVSCVFTNd-----PSNQLRDYDVYQAS-----------DALVI 274 Calothrix sp. P...
WP_015151421 212 Vf--mFR---GKTEKIKSSPASKKKLIY-TTNYLAKLVSCAFAGd-----ANNELREYGVQEAA-----------DALIN 269 Oscillatoria ac...
WP_015956778 212 Vp--mFL---NKTEKIKNSPASKQKLIY-TSNYIAKLASCAFVNn-----DKNELEDYEVEQAS-----------QALIN 269 Gloeothece citr...

WP_015810476 338 I-----------PGISS-----------VDARRDTVAAQPVVLKALAKLTYDFHSEKkrt-wnIPEYQKQLwEAIAS-FD 393 Dyadobacter fer...
WP_015211591 252 VlpndpwrakskEERSV-----------Q--RQELLAVSAVVFQALGMLARELYLEGv----pEEELVKWL-ARLQE-ID 312 Allocoleopsis f...
WP_015172827 252 TlpddpwkvvskKERDR-----------Q--RQETLTVTAVVIQALGLVARDLYVEGv----pDENLMKRL-SRLRE-IN 312 Geitlerinema sp...
WP_012085859 277 Tfpeaw-smpprKSRLT---------------------HGVGIQAMGFVMDALTENTpaaklpDLDLHEPL-QRLREaCA 333 Kineococcus rad...
WP_011838007 253 Lipelh--nyekR---------------AQSKETSLIGENFMFYGYVAISKVLRDKE--------NWKEYL-PLINE-LD 305 Acetivibrio the...
WP_013174404 263 Slpeie--kvvaGKMMP-----------FEHRSRYIAMHSVGWQAMAGAVRAAIDQR------PQDWKDLCrEKFSR-LD 322 Syntrophothermu...
WP_015188357 269 ClnqfflechhtRYIVEkahqnltvddiSRFKEECLLGVSAGLEVLGRLLYHTYAQD------DNYFNQTKiSQLAQ-LD 341 Gloeocapsa sp. ...
WP_015130698 275 ClnsffsecsntEYIADstveeltideiAAFKEDCILGISVGLEVLGRLLHYIYDPE------NNSFNDEKvVQLAQ-LD 347 Calothrix sp. P...
WP_015151421 270 AlnqffgectqtRHIFKtsaedltvdeiDTFKNENLLGRSVGMEILGQLLYCIYDKT------DSCFDPNKvSKLAQ-ID 342 Oscillatoria ac...
WP_015956778 270 ClnqffstchqtQFIAEtrvedltvnqiMEFKEKCILGKSVGLEILGRLLYLTYDKS------NNTFVPEKvSQIAQ-ID 342 Gloeothece citr...

WP_015810476 394 FSHENPAWRYYQLESdeieemgltslesylpsieDGNrdl----gqfSNGMFHFGAKHNDIYPIIGDI 457 Dyadobacter fermentans
WP_015211591 313 WRRSNELWRERGVTQ-------------------VGAtve----piiSNTKTTVDACYKVLREFVGIa 357 Allocoleopsis franciscana
WP_015172827 313 WHREDPFWRERGVTQ-------------------VGAkgd----piiQNTRTTVDACHRVLREFVGvv 357 Geitlerinema sp. PCC 7407
WP_012085859 334 WTSGT--WQ---FGK-------------------SDQrhw----nslQNTPNDVRLLTNYLLRvirs- 372 Kineococcus radiotolerans
WP_011838007 306 LSKGSKQWYGDVI-K-------------------RGKekg----ytiVNNNESRKTFVNKIERMFKKL 349 Acetivibrio thermocellus
WP_013174404 323 WSLNNPAWEGSAMAG-------------------GLV----------ANRAPAIRYLVAQLKEYLGLE 361 Syntrophothermus lipocalidus
WP_015188357 342 WSRENELWRDNIVRI-------------------DLKpknpakpykvSFGGSAIAAAVNTVQVKLGWI 390 Gloeocapsa sp. PCC 7428
WP_015130698 348 WSRENQLWKDNVIRI-------------------DTQpknpekpykiSATVSAVTDAVKIVKITlgwm 396 Calothrix sp. PCC 7507
WP_015151421 343 WSRESPLWKDNVVSI-------------------DPNaknpakrykiTASGNPVRIAINQAKNHLGWi 391 Oscillatoria acuminata
WP_015956778 343 WSISSNLWQGNIVKH-------------------DPNpvntakaykiSGGIIPTKMAVNTAKAALGWq 391 Gloeothece citriformis
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