Conserved Protein Domain Family
DCR
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pfam14047: DCR (This model is not part of the current CDD release)
Dppa2/4 conserved region
This domain has been characterized in the finding of a developmental pluripotency associated gene (Dppa) in the lower vertebrate Xenopus laevis. Previous to this discovery, Dppa genes were known only in higher vertebrates. The domain is subject to structure determination by the Joint Center of Structural Genomics.
Links
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Statistics
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PSSM-Id: 521057
Aligned: 18 rows
Threshold Bit Score: 87.0783
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_003261833 220 GVRWCVVHG--RLLSADTKGWVRLQFHAGQAwVPTTHRRMISLFLLPACIFPSPGIEDNMLCPDCAKRN 286
4_pfamImport   1 GSRWCVVHG--RVLPAETEGWVRLQFHAGQAwVPDSPRRMVSLFLLPACVFPFPDVEDNMLCPEC---- 63 
XP_001742893 136 PRVFCVVHG--A--ICGGEGAMQLQLRGGRVfLGITQQR----FVLTPTASAPEGQADNQLCHTCVVAN 196
XP_007493705 254 SPRWCVVHG--ESFPNDVSGSVPLEFHAGQTwVPEED-MLIPLLLLPACSFPPPGVEDNWLCPKCVCRN 319
5_pfamImport   1 SDKWCVVHG--RTLPANTPGWVQLQFHAGQAwVPEKKGRVSALFLLPSSTFPPPHLEDNLLCPSCVRKN 67 
EGV96790     203 EELWCVVHG--RSFTESTKGWVRLQFHGGQVwVPDKKGKVIALFLLPACNFPPPHLEDNLLCPRCIHR- 268
D3Z8Y2       222 GEMWCVVHG--TSLPATSSGWVRLQFHAGQAwVPDKKGKAIALFLLPACTFPPPHLEDNMLCPKCVHKN 288 Norway rat
3_pfamImport   1 SVWSEVVCGtwEKSPCKHK-WLGSAAHAGQVwVPEKPGRVSALFLLPACNFPPPHLEDNMLCPKCVQRN 68 
Q9CWH0       211 GSRWCVVHG--RQLPADKKGWVRLQFLAGQTwVPDTPQRMNFLFLLPACIIPEPGVEDNLLCPECVHSN 277 house mouse
XP_057344593 217 GVRWCVVHG--RPLLAKKKGWVRLQFHAGQTwVPDTPKKMISLFLLPACTFPSPDMEDNMLCPECVKRN 283 Chinese pangolin
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