pfam14028: Lant_dehydr_C (This model is not part of the current CDD release)
Lantibiotic biosynthesis dehydratase C-term
Lant_dehydr_C is the C-terminal domain of a family of dehydratases that are involved in the biosynthesis of lantibiotics. While the extensive N-terminal domain, pfam04738, is involved in the serine-threonine glutamylation step of the synthetic process, this C-terminal domain, once thought to be a separate domain from the dehydratase enzymic activity, is necessary for the final glutamate-elimination step in the generation of the lantibiotic. Lantibiotics are a class of peptide antibiotic that contains one or more thioether bonds.
Jiyao W et al.(2023). "The conserved domain database in 2023.",