Conserved Protein Domain Family
PgaD
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pfam13994: PgaD 
PgaD-like protein
This family includes the PgaD protein from E. coli. The homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (beta-1,6-GlcNAc; PGA) serves as an adhesin for the maintenance of biofilm structural stability in eubacteria. The pgaABCD operon is required for its synthesis and export. It has been shown that PgaD is essential for this process.
Links
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Statistics
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PSSM-Id: 493871
Aligned: 14 rows
Threshold Bit Score: 108.358
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q3A0T3         6 IIEKPEAQNRGQRLAQGVLTVGFWCLFLSLLRPLLTLFAWLIGIRLFTYEMIe----------kDGGRLLLEALRNYGLV 75  Pelobacter carb...
WP_012636726  11 IIERADLEPKGKRYLGRFINLLGWAIWTYLFTPLIALIGWFLGFELFQRHIL------------DDPMGTLRAIQTYAII 78  Thioalkalivibri...
WP_013817278   6 IIDSPTLQSVRQRYLSATFTFVFWVIWIFLWTPLITLLGWFFGLDLVYIEMIk----------lEGYKSVIADFGLFLIC 75  Methylomonas me...
WP_013146752   6 IIEKPELQSHAHRFGWSSITLFFWGLYIYLWLPFITLLAWWIGVKLFHLQIVe----------lHGYAGVIGKLGLYSAI 75  Methylotenera v...
WP_013148426   6 IIERPELQSMTQRYGWKSVTFFFWMFYIYLWVPLITLVVWLVGVKLFHINMIe----------fNGYESLVDKLGLYSAI 75  Methylotenera v...
Q7NTW3        14 IISAVHNVPWWRRLLGWLVTLAFWCVWFYLWLPLLVSLARLGGMRVPVPGWVrg----------iGWVHSRHLLILYALA 83  Chromobacterium...
Q30SJ9         8 IINQRHELPFSKKIGWDIVTILLWAGWIYLWKPLLIVFYNIVTLDAHVDEISkvifdeisavtvEHA----------LLM 77  Sulfurimonas de...
Q6FDD7         9 IIDLRRQLPWHKRYVSMTTTAMMWGGWLLLWRPFLLV---WLLVELQKTHLVhrvfsamslgleHG-----------ITA 74  Acinetobacter b...
WP_014087075   6 IINARHHLRWHQRLLSNASTAVAWAGWLYLWRPIVNGANWLTSWGASYQQLLaktlstgssgslENS----------VVA 75  Pseudogulbenkia...
Q2IDN4         6 IINARHRLAWYQRLLSDASTAVMWGAWLWLWVPVVRA---IAELGMRSSPVLvklvasgtagdlPSS----------VVA 72  Anaeromyxobacte...

Q3A0T3        76 VLVLAVILRTWAWYNHRRFAGREkRRNTMPP-LSTDEITGYYGVDPTALAMWRKDGSLYVRHNKEGKVL 143 Pelobacter carbinolicus DS...
WP_012636726  79 IVSAAVIFVAWAGYNWFRYHGKQ-RRHAPAA-VGTEELARHFGIARDDARKIAREPIVTVHFDDDARII 145 Thioalkalivibrio sulfidiph...
WP_013817278  76 VTGIGGILGIWAAYNFFRFKDLE-RRAALDP-VNNRQLATFFGVDPQILAKQQKAQCLSVSFDSQGHII 142 Methylomonas methanica
WP_013146752  76 VVILSVTLIGWANIERFRFKDSA-RRVDNTP-VSVREIAKLFKLQENQLIQLRQKQSVIVRFSDKGHLT 142 Methylotenera versatilis
WP_013148426  76 ILIISIILIGWAEVNRMRFKNKL-RRLDNNE-LSVGEVAKKYNLEVSHLTLLRQKKSVKVDFSAKGGIS 142 Methylotenera versatilis
Q7NTW3        84 AALIGGALLLWAAINLWRFAGVN-RRGQIPA-VAEREVAQALGIAETELARGRRSKVCIARHQDDGWLe 150 Chromobacterium violaceum
Q30SJ9        78 LVATPTVLFILSWLNRH-------VAPSEHFiYKFDEYANYFKVDSTKLRETMDSQLITIYHDDNGHIA 139 Sulfurimonas denitrificans...
Q6FDD7        75 LIICSVSLLLWSNYIPAKSVKKIkQK-------DLNDYAGYFELNQQQIQLGRTQKVAIVHHDENGRIT 136 Acinetobacter baylyi
WP_014087075  76 LLGTSGTLLLWSQLPSRKPKATAhQL------ETLESYANHFGMGEQQILAGRAASVCVVHHDSHGKII 138 Pseudogulbenkiania sp. NH8B
Q2IDN4        73 LVGTSGTLLVWKGLPARKALADGeAL-------SLRDYARHFALPESSLQAGRRAAVCVVHHDDDGRIV 134 Anaeromyxobacter dehalogen...
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