6OCE


Conserved Protein Domain Family
RSN1_TM
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pfam13967: RSN1_TM (This model is not part of the current CDD release)
Late exocytosis, associated with Golgi transport
This family represents the first three transmembrane regions of 11-TM proteins involved in vesicle transport. In S. cerevisiae these proteins are members of the yeast facilitator superfamily and are integral membrane proteins localised to the cell periphery, in particular to the bud-neck region. The distribution is consistent with a role in late exocytosis which is in agreement with the proteins' ability to substitute for the function of Sro7p, required for the sorting of the protein Enap1 into Golgi-derived vesicles destined for the cell surface.
Links
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Statistics
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PSSM-Id: 521017
Aligned: 127 rows
Threshold Bit Score: 97.6346
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6OCE_A         10 SAAINVSMAVAFLLVFAFLRlqPINDRVYFPKWYlrgmrDSPVsSgaavqkvvnlnmrSYLKFLSWMPAALKMPEDELIN 89   Japanese rice
XP_002480090   43 SLATSLGISALLALLFSLFR--PYHNAIYAPKVKha-dqKHAPpP-------------VGKGVFAWVPPVLSVKEQDLAD 106 
Q4WY38         38 SLGASAGISILLALLFSLFR--PRHTLVYAPKVKha-drRHTPpP-------------VGKGFFAWMRPVLRTREPELVE 101  Aspergillus f...
6_pfamImport    5 AVGTSFGMTAAIFIGFILLR--PFNTIVYAPRLRhs-deKHRPpP-------------LDKSLFAWYRPVFKTNEPEYVE 68  
XP_001903428   30 ALGSSIGTTAVIAFLFSILR--PFNSVVYAPKLKha-deKHAPpP-------------MGKGFFAWVTPLWKTTEEDMVN 93  
Q7S914         41 ALGSSVSITVAVALGFSLVR--PLNTVVYAPKLKha-ddKHAPpQ-------------LGKGFFSWIKPLWTTTEQDLVR 104  Neurospora cr...
Q2GZW7         39 ALGSSLGVTAAIAICFSFLR--PYNSVVYAPKLKha-deKHAPpP-------------LGKGVFAWVVPLWSTSELDMIN 102  Chaetomium gl...
XP_003042255   43 ALAISLPVTIFIAFCFSLLR--PYHQAIYAPKMKha-deKHAPpP-------------IGKAPWSWITTLWKTKEEQLVY 106 
XP_003003836  202 ALGTSVLFTLGIAIAFSFLR--PYNQSVYAPKTKha-deKHAPpP-------------IGRKLWSWVFPLWSTTEYEFIQ 265 
XP_011390374   43 TIVAFVALSLFTLIAFQILR--PNNKIVYAPKYKya-eeGKAPpK-------------ASEGFFGWIPPILKYKEHDLLP 106 

6OCE_A         90 HAGLDSAVYLRIYLTGIKIFVPISILASlVLFPVNWTNDTLDSMKVv---hSkidklsisnipYGSNRFVTHLVMAYAVT 166  Japanese rice
XP_002480090  107 RIGLDAVIFLRCAKVMRNIFLVLSVIGCgILIAVNITQSNG-SAVPgtsaftl----mtplyiLT-DAVWAQVVCAYIFD 180 
Q4WY38        102 CIGLDATVFLRFTKMCRNIFIILSIIGCgVMIPVNLTQSNGSGISSlsafat------mtplyvTTEAIWSQVICAWAFD 175  Aspergillus f...
6_pfamImport   69 KIGLDATIFLRFARMCRNMFIVLAVVGCgIIIPVNIANSVEFQKKFdtnlrGniiflmtprdlFG-RVFWAFVILAYIID 147 
XP_001903428   94 LIGMDATIFMRFTRMCRNIFAILTVLGCaILIPVNWTAT----TRVgi--eDnwlskitpnlvWG-SAQWASVSVAWIFD 166 
Q7S914        105 LVGMDATIFMRFTRMCRNIFLCLAVLCCcIQIPINWYKNAAPES-------Pwlqkv-tpmnvWN-QWQWATVVMSWVTT 175  Neurospora cr...
Q2GZW7        103 LVGMDAALFIRFTRMCRNIFLVLSVLGCaILIPIYWV------NFAae--eAswvtritplnvWA-SSHWATVTFAWLLT 173  Chaetomium gl...
XP_003042255  107 LIGMDATIFLRFVRMCRNMFLTLCVTGVgILLPVHVSHWKKIGDDSgntwvsk----itplhvWGQ-AIWAQVVIAWAFN 181 
XP_003003836  266 YAGMDAAIFMRFVEMLRNLFVTLTVFVLaILIPVNLTQV----DVSge--gRawlamltpsnvWG-DAQWAQVTVAYGIN 338 
XP_011390374  107 LIGLDGVTFLRFVRMMRWMLTTLALLMSvVLMPVDIAYNVRNGGSNlv--tNrlnyl-nmsnvHGT-YMWAHVGMSYVGT 182 

6OCE_A        167 FWTCYVLFRE 176  Japanese rice
XP_002480090  181 IVIMFFLWKN 190 
Q4WY38        176 IILAYFLWRN 185  Aspergillus fumigatus
6_pfamImport  148 VIVCAFLWWT 157 
XP_001903428  167 IVVCVFLWWN 176 
Q7S914        176 LIVCFFLWWn 185  Neurospora crassa
Q2GZW7        174 AVVCGFLWWN 183  Chaetomium globosum CBS 148.51
XP_003042255  182 IIIAIYLWFN 191 
XP_003003836  339 AIVMFFLWWN 348 
XP_011390374  183 IVALSFIWYH 192
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