Conserved Protein Domain Family
Kelch_5

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pfam13854: Kelch_5 (493751 is an unknown moldel)
Kelch motif
The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Drosophila ring canal kelch protein is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.
Statistics
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PSSM-Id: 493751
Aligned: 56 rows
Threshold Bit Score: 31.7774
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003721217  297 PLPRTRHCVVAArsggsgS-YEIFVYGGASAlklSENQGFADLH---IL---TVPGF 346 
XP_002676247  805 PRSVYNVFIEII------D-KTMYFFGGRV----NRVQSVGDIH---VA---SLADW 844 
XP_002676251  637 PVPLYSAFIEVV------G-DYIYLFGGSTT------FESSSFN---IF---RATTE 674 
Q12S85         59 PVAVDDSAVASY------QdRYIYLFGGWHQ-----DGNVNLEQ---VY---DTHTD 98   Shewanella denitrificans OS217
XP_002676169  513 PVSIYNSHFLKA------D-EYVYFFGGFI-----NDEVSNKIYrapIY---DVESG 554 
A0D447        333 PIISYGGQAIKQ------G-QFIYYWGGYILv-dNVSIGNKKGF---KY---LINGN 375  Paramecium tetraurelia
3_pfamImport    2 PDSIHNSHFFKH------N-EEMYLFGGIV-----NNNVSNAIY---KC---PLYDL 40  
XP_002676179  400 PVSIYSTHYLKL------D-EYVYFFGGFI-----NDHLSNAVY---RApysDVETG 441 
XP_001997302   58 PNGCAAYGFVVE------G-TRMFVFSGMI----EYGKYPNELY---EL---QAIKW 97  
Q97Z97        186 PVPTYGGGYVFN------G-TSLIIVSGYIG----YSAYTNDIL---IY---SPQNN 225  Saccharolobus solfataricus P2
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