8JYC,2WL1,5ZZ3,3KB5


Conserved Protein Domain Family
PRY
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pfam13765: PRY (This model is not part of the current CDD release)
SPRY-associated domain
PRY is a 50-60 amino acids domain associated with SPRY domains, adjacent to its N-terminal. PRY and SPRY domains are structurally very similar and consist of a beta sandwich fold. Distant homologues are domains in butyrophilin/marenostrin/pyrin, evolutionarily more ancient than SPRY/B30.2 counterpart.
Links
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Statistics
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PSSM-Id: 520897
Aligned: 91 rows
Threshold Bit Score: 52.1272
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8JYC_A        21 VVLDPDTAHPDLFLSEDRRSVRRCPFRHlgeSVP--DNPERFDSQPCVLGRESF 72  human
Q5SZ99       296 VILDPSTAHLDLALTKGGRLVTYKRCPR---DLQarSSAKRFYGLPCVLGCEGF 346 house mouse
NP_001124100 269 VILDPDTAHPKLILSEDGKQVRYGNIKH---DRP--GSDKRFENYIVVLGKEGF 317
Q495X7       297 VILDLNTAHPQLLVSEDRKAVRYERKKR---NIC--YDPRRFYVCPAVLGSQRF 345 human
Q8VI40       292 VTFDRDTAHPQLVISEDRKSVFYKEAWP---CVC--ASPQKFHLWPALLGCKGF 340 house mouse
Q6UX41       290 VTLDPETAHPKLCVS-DLKTVTHRKAPQ---EVP--HSEKRFT-RKSVVASQSF 336 human
A6NK02       296 IILDPETAHPNLIVSEDKKRVRFTKRKQ---KVP--GFPKRFTVKPVVLGFPYF 344 human
Q8JZK6       283 VILDPETANYKLTVSKDKKTVKYGSWE----RVP--YSSRKFCFDPAVLGSEGY 330 house mouse
XP_034503591 235 VTLDPKTAHPCLVLSEDLRSVSLRNVQQ---DIP--GSPGRFVFGATVLGVEGF 283
O77666       315 VTLDPQSASGYLQLSEDWKCVTYSGLYQ---SSY--LHPQQFECEPGVLGSKGF 363 pig
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