Conserved Protein Domain Family
SurA_N_2
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pfam13623: SurA_N_2 
SurA-like N-terminal domain
This domain is found at the N-terminal of the chaperone SurA and related proteins such as PpiD and foldase PrsA. This is a helical domain that together with the C-terminal forms a domain containing substrate-binding sites. The C-terminal of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.
Links
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Statistics
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PSSM-Id: 493554
Aligned: 137 rows
Threshold Bit Score: 82.2413
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
CDA43938       4 LQSIRSKGA-LLVGA-LGLALFAFIaeeFFRSLETTSNM-DRNIVGEVYGEKLNIQDFQQMVDEQSE----VAKMQmrmQ 76 
WP_012970637   2 LQTIRERAQgWIAWAiVILISIPFA---LWGIQSYLGVG-GEPIAATVNGVEIPARELDRRVQETRF----ELRER---L 70  Allochromatium ...
WP_014777184   2 LQTIRDRAQgWIAWAiVVLISVPFA---LWGIQSYLGVG-GEPVVAKINGVEIPARELDRRVQEARI----ELRER---L 70  Thiocystis viol...
WP_014705053   2 LHYIREKAQgWVAWLiVGLISIPFA---LWGLDSYLTGE-SSVTVATVNGEDISQSDLQAALQQYRD----QMRSS---M 70  Methylophaga fr...
WP_013031869   2 LEAIRSRAQgIFAWViVGLITIPFA---LWGINNYFREG-GEALAASVNGEEITTREFRAAFQRYTQ----QLRFL---M 70  Nitrosococcus h...
Q3JAA3         2 LEAIRNRAQgIFAWViVGLIAIPFT---LWGINNYMLDG-GEALAASVNGEEISTREFRSAFLSYTQ----QLRFL---M 70  Nitrosococcus o...
2_pfamImport   1 LQNIRDNSQgWIAKTiIGVIVVLLA---LTGFDAIFNAAsNAQNAAEVNGEEISRYDLDQAMNMQRR----QLAQQ---L 70 
Q87YS0         2 LQNIRDNSQgWIAKTiIGIIIALMA---FTGIEAMFTATsNKQNAAEVNGEDITQNELSQAVDMQRRqlaqQLAQQ---L 75  Pseudomonas syr...
Q88KI6         2 LQNIRDNSQgWIAKTiIGLIVVLMA---LTGFEAIFQAAtHSQDAAKVNGQTISQNELSQAADMQRR----QLMQQ---L 71  Pseudomonas put...
WP_012637517   2 LQKIRDKATgWIAYViVILISIPFA---LWGLNEYFGGA-PAQVVAEVNGVEIPARAYQQEFQQQRQ----QLAQM---F 70  Thioalkalivibri...

CDA43938      77 GQDGTLNDQQTEQIREQVWQQFVQKSMIEHECDKLGLFVTDGEVQEALRQgdAQSlqmmtmfFRnqQTGRFDLQGLQDFM 156
WP_012970637  71 GAAYDPAAFDDQRLRAEVLETLIQEALLMDVVGRLGLRVSDQEVQMQILS--DPA-------FV--SEGRFDKDTYERLL 139 Allochromatium ...
WP_014777184  71 GAAYDLAALDDKQLRAEVLDEMVREVLLLDVTRRLGLRVSDREIQIQVLS--EPA-------FQ--QDGRFDQGAYERIL 139 Thiocystis viol...
WP_014705053  71 GEEFDPAMFEGSSMRFAVVQDLIDQRLLEKASDELGQRIADSEIANIVRQ--TEV-------FQ--VDGQFNMAHYQTVL 139 Methylophaga fr...
WP_013031869  71 REGFSEEMLDDPATKQRVLEGLIEQRLVLDAAGELGLGMSDSELSKVIHN--NEA-------FQd-ETGQFDFQRYESVL 140 Nitrosococcus h...
Q3JAA3        71 GASFPEEMLDDPATKQNVIEGLVEQRLVLDTAAKLGLGMSDSSLSQVIRS--NKA-------FQg-ESGQFDSQRYEAVL 140 Nitrosococcus o...
2_pfamImport  71 GQDFDPSLLDDRLLRDAALGSLIDRMLLLQAAKGANFAFSREALDQLILQ--TPE-------FQ--VDGAFNPARFDQVI 139
Q87YS0        76 GKDFDPAMLDEKLLRESALKGLIDRKLLLQGAGDARFSFSDAALDQQLLQ--TPE-------FQ--VDGKFSADRFDQVI 144 Pseudomonas syr...
Q88KI6        72 GKDFDPALLDDKLLREEALKGLISRKLLLQGAEDAKFAFSEAALDQVILQ--TPE-------FQ--VDGKFSAERFDQVI 140 Pseudomonas put...
WP_012637517  71 GGRIPSGAVDENMMRENALQTLIRRELVAQMAEDKGFRISASAVASEIRA--VPG-------FQ--RDGVFDPERYRQIM 139 Thioalkalivibri...
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