Conserved Protein Domain Family
HTH_Tnp_4

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pfam13613: HTH_Tnp_4 
Helix-turn-helix of DDE superfamily endonuclease
This domain is the probable DNA-binding region of transposase enzymes, necessary for efficient DNA transposition. Most of the members derive from the IS superfamily IS5 and rather fewer from IS4.
Statistics
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PSSM-Id: 493545
Aligned: 53 rows
Threshold Bit Score: 50.6167
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EFN73369       33 VRM-NTRDRVIMTYMKLKQNVSYSLLAIIFNCySAKHCQRVFYNTVKILNKCLKP 86 
jgi:Amir_0183  55 RKL-NPGQQALLVLVYLRKGETFADLAAGFAV-STSTCWRYVNETVELLAQRSPK 107
WP_012783212   34 RRL-DPGRQALLVLAHLRCGDTYTRLAVGFGV-GLATVCRYIHEAVELLAALAPD 86  Actinosynnema mirum
WP_011713120   58 HALpDLENHLLALMLYYRARVTYYLIGNWLGV-NETTALRRIKWIEPLVKQRGKL 111 Magnetococcus marinus
Q8DN37        106 PKL-SLEDLLMATLQYVREYRTYEQIAADFGI-HESNLIRRSQWVEVTLVQSGvt 158 Streptococcus pneumoniae R6
WP_013190579   47 KPLlGIQEQVLVTLEYWREYRTYFHIATSWRV-SESTICRIVHRIESELVQSGMF 100 Trichormus azollae
ACP21072       47 HKLc-MEDQLLMALEYLREYRTYFHIAQSYGI-SESSAYKGIKWIENTLIKHPAF 99 
ACP20843       59 NKLs-CEQMLLMTLEYLREYRTYFHISKSYGI-SESNCYYTIRFIEEALIKSGQF 111
CCB86563       47 KKL-SVENMLLMALEYIREYRTYFHISQSYSI-SESNAYKTVKWVEDTLIKHPdf 99 
jgi:Gobs_1999  58 YRL-VFLDRLLATLVHLRHGVTHDVLACWFGV-SRSTITRAVGEVRPLLAERGCT 110
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