3EH7,3D3U,3QLI


Conserved Protein Domain Family
AcetylCoA_hyd_C
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pfam13336: AcetylCoA_hyd_C (This model is not part of the current CDD release)
Acetyl-CoA hydrolase/transferase C-terminal domain
This family contains several enzymes which take part in pathways involving acetyl-CoA. Acetyl-CoA hydrolase EC:3.1.2.1 catalyzes the formation of acetate from acetyl-CoA, CoA transferase (CAT1) EC:2.8.3.- produces succinyl-CoA, and acetate-CoA transferase EC:2.8.3.8 utilizes acyl-CoA and acetate to form acetyl-CoA.
Links
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Statistics
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PSSM-Id: 520675
Aligned: 147 rows
Threshold Bit Score: 147.984
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3EH7_A        276 GSEDVYHFI-----D-----KNPDVELYPVDYVN---------D---PRVIA--QNDNXVSINSCIEIDLXGQVVSECI- 330 Porphyromonas ...
Q3JAD8        444 GPQRFYNFLrglkkE-----EREQFCMKRVAYVNqly----gsE---ELKRL--QRKDARFLNSALMVTLNGAIISDKLe 509 Nitrosococcus ...
Q6LQ13        472 GPKDFYEAL-----NtmtdaEHDQFCMTSVNYVNelydhflgsQ---QLKQA--QRKHARFINSAMMVTLNGSVISDALe 541 Photobacterium...
jgi:Dole_1004 447 GANRFYAYLrrmseE-----ERKQFIMTGVAYVNqly----gdE---TIKRL--QRKDGRFINAGMKVTLMGHVASDALe 512
WP_012609294  441 GPNGFYDFLrdmsdE-----ERKKFEMTGVKVVN---------QlygDEVLRslERKDARFVNAGMKISLMGNVASDALr 506 Desulfatibacil...
2_pfamImport    1 GSTAFYAWLremdsQ-----TRAGIGMHRISEINqly----gnE---TLRRL--QRRQARFFNSCMMVTALGAAVSDALd 66 
WP_012827786  437 GSRRFFERLralpeA-----ERRRIFMTGVDRVNqla---pgrE---ALSRA--QRQRARFVNTCMKMTLTGAAVSDTLs 503 Haliangium och...
Q0VNK9        436 GPRDFYARLlemskQ-----EHAQINMTRISFINhly----gdE---ILKRL--QRQDARFVNTAFTVTLLGAVASDQIe 501 Alcanivorax bo...
Q88BB0        361 GPSSFYERLrelpaE-----RLAQFNMTAISYINely----gqE---DLKRL--QRRDARFINSAFTVTLMGAAVADQLe 426 Pseudomonas sy...
Q2SL76        439 GPQRFYDML-----HglsdeEHQKFCMTSVNFINhlydhkfgvQ---ALKVA--QRAESRFINSAMMVTLNGAVISDGLs 508 Hahella chejue...

3EH7_A        331 GSKQFSGTGGQVDYVRGAAWSKNGKSIXAIPSTAK--N-G--TA-SRIVPIIAegaAVTTLRNEVDYVVTEYGIAQLKGK 404 Porphyromonas ...
Q3JAD8        510 DGRTVSGVGGQYNFVAMAHALVDARSIIMLRSVRE--KhG--EIhSNIIWNYG---HTTIPCHLRDMVVTEYGIANLRGK 582 Nitrosococcus ...
Q6LQ13        542 NGQVVSGVGGQYNFVAQAHQLPGARSILKLRSCCV--R-Gg-KLqSNILFNYG---HTTIPRHLRDTVITEYGIADLRSK 614 Photobacterium...
jgi:Dole_1004 513 NGTVISGVGGQYNFVSMAHALEDARSILMVRSTKDlaH-G--VD-SNVVFNYG---HTTIPRHLKDIVVTEYGIADLRGK 585
WP_012609294  507 NGTVISGVGGQYNFVSMAHALPDARLIMMLRSTKE--TpK--EVkSNILFNYG---YTTIPRHLRDIVVTEYGIADLRSK 579 Desulfatibacil...
2_pfamImport   67 DGRVVSGVGGQYNFVAMAHALEDARSVLMFRATRG--N-GgtTH-SNVRWNYG---HTTIPRHLRDLYVNEYGIADLRGL 139
WP_012827786  504 DGQVVSGVGGQYNFVAMGHALPGGRSVLMLRSTR---G-G---D-SNIVWEYA---QQTIPRHLRDLVVTEYGIADLRGK 572 Haliangium och...
Q0VNK9        502 NGRVLSGVGGQYNFVSQAHELEGARSILMVRAWRE--RaG--EVmSNIVFSYG---HNTIPRHLRDIVITEYGVADLRGK 574 Alcanivorax bo...
Q88BB0        427 DGRVLSGVGGQYNFVAQAHALEGARSILMLRSWRE--S-Gg-EVsSNIVWQYG---HTTIPRHLRDIVVTEYGIADLRGQ 499 Pseudomonas sy...
Q2SL76        509 NGKVVSGVGGQYNFVAMAHEIPQARSIIKLKSTRN--S-GgrTL-SNIIFNYG---HMTIPRHLRDIFVTEYGIADVRGK 581 Hahella chejue...

3EH7_A        405 SLRQRAEALIAIAHPDFREELTKH 428 Porphyromonas gingivalis
Q3JAD8        583 NDREIIIALLNITDSRFQDFLLRE 606 Nitrosococcus oceani ATCC 19707
Q6LQ13        615 SDHVVYTELIKIADSRFQQELLEK 638 Photobacterium profundum
jgi:Dole_1004 586 VDSQVVKCLLNIADSRFQPELLEK 609
WP_012609294  580 QDWVVMTELIKVADSRFQDELLDE 603 Desulfatibacillum aliphaticivorans
2_pfamImport  140 SDEDCIAAMLGIADAQAQPALLAE 163
WP_012827786  573 TDEECVKALIAISDASVHERLRRV 596 Haliangium ochraceum
Q0VNK9        575 TDEEVVMAMLNVADSRFQIELMEQ 598 Alcanivorax borkumensis SK2
Q88BB0        500 TDATVIERILNISDSRFQPGLIEQ 523 Pseudomonas syringae pv. tomato
Q2SL76        582 SDKDVFIELIKVADSRFQDELLQQ 605 Hahella chejuensis KCTC 2396
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