3EH7,3D3U,2OAS,4N8K


Conserved Protein Domain Family
AcetylCoA_hyd_C
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pfam13336: AcetylCoA_hyd_C (This model is not part of the current CDD release)
Acetyl-CoA hydrolase/transferase C-terminal domain
This family contains several enzymes which take part in pathways involving acetyl-CoA. Acetyl-CoA hydrolase EC:3.1.2.1 catalyzes the formation of acetate from acetyl-CoA, CoA transferase (CAT1) EC:2.8.3.- produces succinyl-CoA, and acetate-CoA transferase EC:2.8.3.8 utilizes acyl-CoA and acetate to form acetyl-CoA.
Links
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Statistics
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PSSM-Id: 493298
Aligned: 144 rows
Threshold Bit Score: 149.909
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3EH7_A       276 GSEDVYHFI-----DKNPDVELYPVDYVN------D---PRVIA--QNDNXVSINSCIEIDLXGQVVSECI-GSKQFSGT 338 Porphyromonas g...
WP_011995087 328 GSRAFYEKLrampqEMRDKIAMVPVAYVNdlh-gdE---ERKRA--ARQKARFVNTAMMATLTGAVVSDGLeDGRVVSGV 401 Parvibaculum la...
Q3JAD8       444 GPQRFYNFLrglkkEEREQFCMKRVAYVNqly-gsE---ELKRL--QRKDARFLNSALMVTLNGAIISDKLeDGRTVSGV 517 Nitrosococcus o...
WP_012174432 447 GANRFYAYLrrmseEERKQFIMTGVAYVNqly-gdE---TIKRL--QRKDGRFINAGMKVTLMGHVASDALeNGTVISGV 520 Desulfosudis ol...
WP_012609294 441 GPNGFYDFLrdmsdEERKKFEMTGVKVVN------QlygDEVLRslERKDARFVNAGMKISLMGNVASDALrNGTVISGV 514 Desulfatibacill...
4_pfamImport   1 GSTAFYAWLremdsQTRAGIGMHRISEINqly-gnE---TLRRL--QRRQARFFNSCMMVTALGAAVSDALdDGRVVSGV 74 
WP_012827786 437 GSRRFFERLralpeAERRRIFMTGVDRVNqlapgrE---ALSRA--QRQRARFVNTCMKMTLTGAAVSDTLsDGQVVSGV 511 Haliangium ochr...
Q0VNK9       436 GPRDFYARLlemskQEHAQINMTRISFINhly-gdE---ILKRL--QRQDARFVNTAFTVTLLGAVASDQIeNGRVLSGV 509 Alcanivorax bor...
Q88BB0       361 GPSSFYERLrelpaERLAQFNMTAISYINely-gqE---DLKRL--QRRDARFINSAFTVTLMGAAVADQLeDGRVLSGV 434 Pseudomonas syr...
WP_012563792 334 GPKSFYRALremppDRLDRIRMMPVSFTNaly-gdE---DRKRR--GRPKARFVNNAMMVTLLGEAVSDGLsNGQVVSGV 407 Afipia carboxid...

3EH7_A       339 GGQVDYVRGAAWSKNGKSIXAIPSTAK--N-G--T--A-SRIVPIIAegaAVTTLRNEVDYVVTEYGIAQLKGKSLRQRA 410 Porphyromonas g...
WP_011995087 402 GGQYNFVAQAFALEDARSVIAVRATRN--KdGk-T--A-SNIVWSYG---HMTIPRHLRDVIVTEYGVADLRGKTDGEVV 472 Parvibaculum la...
Q3JAD8       518 GGQYNFVAMAHALVDARSIIMLRSVRE--KhG--E--IhSNIIWNYG---HTTIPCHLRDMVVTEYGIANLRGKNDREII 588 Nitrosococcus o...
WP_012174432 521 GGQYNFVSMAHALEDARSILMVRSTKDlaH-G--V--D-SNVVFNYG---HTTIPRHLKDIVVTEYGIADLRGKVDSQVV 591 Desulfosudis ol...
WP_012609294 515 GGQYNFVSMAHALPDARLIMMLRSTKE--TpK--E--VkSNILFNYG---YTTIPRHLRDIVVTEYGIADLRSKQDWVVM 585 Desulfatibacill...
4_pfamImport  75 GGQYNFVAMAHALEDARSVLMFRATRG--N-GgtT--H-SNVRWNYG---HTTIPRHLRDLYVNEYGIADLRGLSDEDCI 145
WP_012827786 512 GGQYNFVAMGHALPGGRSVLMLRSTR---G-G-----D-SNIVWEYA---QQTIPRHLRDLVVTEYGIADLRGKTDEECV 578 Haliangium ochr...
Q0VNK9       510 GGQYNFVSQAHELEGARSILMVRAWRE--RaG--E--VmSNIVFSYG---HNTIPRHLRDIVITEYGVADLRGKTDEEVV 580 Alcanivorax bor...
Q88BB0       435 GGQYNFVAQAHALEGARSILMLRSWRE--S-Gg-E--VsSNIVWQYG---HTTIPRHLRDIVVTEYGIADLRGQTDATVI 505 Pseudomonas syr...
WP_012563792 408 GGQYDFVAQAFALEGARSILTLEATRH--N-G--KrlE-SNIRWSYD---HTTIPRHLRDIVVTEYGVAELRGKSDAEVI 478 Afipia carboxid...

3EH7_A       411 EALIAIAHPDFREELTKHL 429 Porphyromonas gingivalis
WP_011995087 473 AEMLSIADSRFQPELLAQA 491 Parvibaculum lavamentivorans
Q3JAD8       589 IALLNITDSRFQDFLLREA 607 Nitrosococcus oceani ATCC 19707
WP_012174432 592 KCLLNIADSRFQPELLEKA 610 Desulfosudis oleivorans
WP_012609294 586 TELIKVADSRFQDELLDEA 604 Desulfatibacillum aliphaticivorans
4_pfamImport 146 AAMLGIADAQAQPALLAEA 164
WP_012827786 579 KALIAISDASVHERLRRVA 597 Haliangium ochraceum
Q0VNK9       581 MAMLNVADSRFQIELMEQA 599 Alcanivorax borkumensis SK2
Q88BB0       506 ERILNISDSRFQPGLIEQA 524 Pseudomonas syringae pv. tomato
WP_012563792 479 AAMLCVADSRFQDDLMRQA 497 Afipia carboxidovorans
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