Conserved Protein Domain Family
SocA_Panacea
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pfam13274: SocA_Panacea 
Antitoxin SocA-like, Panacea domain
This domain is found in Antitoxin SocA from Caulobacter vibrioides and in similar proteins widespread across bacteria, archaea and tailed bacteriophages. SocA is the antitoxin component of an atypical type II toxin-antitoxin (TA) system which neutralises the toxic activity of toxin SocB by acting as an adapter to promote its degradation by the protease ClpXP.
Links
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Statistics
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PSSM-Id: 493245
Aligned: 66 rows
Threshold Bit Score: 48.9441
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
jgi:Igag_0774  27 LQKLLFLVEHLDLssrrVVKSTGLTGYKFYIWLYGPFsE----EVYK----DLEtlvnredii-eevigadtrIRVDEAG 97 
BAF61052       27 LAKLILFAEIEHF----QRTGDSVTGLYFVRMKMGPV-IaffdEVLKdgegELWdkkttpipi-yeerkekfqYCYAPKR 100
Q5V010         39 LQKLIYLAELMYRe---KHEGRPLTEAEYKPYMYGAYsE----DVDD----TLSelrgdpevk-aenqhryrnSKTTYKG 106 Haloarcula mar...
CCY76632      222 LMKMLWYADSLSF----KFYGHAMTGLVYCHEDMGAL-P----VGHY----KIg------------------gLQFVNME 270
jgi:Slip_1338 188 LMKHLWFSDFRCF----RETSTSISGALYAALPHGPA-L----HKWE----VLLgiaqd---------rgfvnIEV---- 241
WP_013875446   48 aNKVLYFAEFAHV----RETGLPITGVRYRKLERGPA-PrhlrAIRD----HLIdngdavlikervlgyeqhrLRPTRPA 118 Protofrankia
jgi:Elen_2797 180 LNKVLFYLDFAAY----RDSGEGFTGLRYAKAPFGPV-P----DRFE--------------------------LLVAGLV 224
WP_013446502  125 LYKLLYFSDFNYY----ELYEEHLTGAKYRKLPYGPV-PqkleSIIHq-------------------------MIEQDKI 174 Paludibacter p...
WP_020457843   25 V-KMLYLFEYYHV----QTFGEQYAELTFIRYNYGPYaQaieiALDD----LMNdglikreiv-eytdrciylHTLCDTG 94  Acetivibrio th...
WP_014585674   26 LTKLVYLSDWRHC----LRTNSQISNIKWFFNNFGPFvW----DIKD----TAKenphifeletttnmygdqkTIFILNS 93  Methanothrix h...

jgi:Igag_0774  98 VVLPLYdDDEAPkviyiyqprtsilqrflggrdkveINERVKEKIEWVLKEFGKL-RPSELEDITM 162
BAF61052      101 EAE---------------------------------LSEEVQETVNIVCKKYGWK-TGTELSRLSH 132
Q5V010        107 EIEDLD------------------------------IPSDVEDLVEVVTNMTRRM-SSDDLAQWSK 141 Haloarcula marismortui
CCY76632      271 E----EcDYENVkyhflpn----------dkldeseLSAEEKEILDKVIEKFESY-TAQQIIEYMH 321
jgi:Slip_1338 242 -----EyLGEFEvemvraa----------refdgsvFTPTEIEIMGEVKSEFQGL-SARELSEISH 291
WP_013875446  119 RREL--------------------------------FSATELKAVQDAVNLLRGH-TNADASERSH 151 Protofrankia
jgi:Elen_2797 225 DDEALAlREQGDgqvivag----------raedptcFSASDLSLLDAVCSFANGFaSTSALSEFSH 280
WP_013446502  175 KRFKSEyHGFPQtryiplv-----------kadltnLKASEKEIIDRVIEQMSDW-SASAISNYSH 228 Paludibacter propionicigenes
WP_020457843   95 KTYTDL------------------------------LNEEKKLIADRVIGELSNK-NYDDMIKHVY 129 Acetivibrio thermocellus
WP_014585674   94 KDYSPR------------------------------LSEEEMKSIDHVINETKNL-NWDQFIRLVY 128 Methanothrix harundinacea
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