Conserved Protein Domain Family
clamp_Gag1-like
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pfam13259: clamp_Gag1-like (This model is not part of the current CDD release)
Gag1-like, clamp domain
This domain found in a group of sequences from fungi and plants, including Gag1 from Saccharomyces cerevisiae, which interacts with Cka2, the fourth subunit of the eukaryotic kinase CK2. Gag1 is organised into three domains: lock, Gag and Clap (this entry). This domain has three regions: rear, hinge and front. It contains two conserved sequence motifs: IPL and FLVD.
Links
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Statistics
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PSSM-Id: 520637
Aligned: 82 rows
Threshold Bit Score: 87.3359
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EPE07745     198 SPFRFD---------SPDA--VGGAAAkna---tpdERKAKARRDVRAEMAWNDGLACFNARRDAWT-------GAQTVR 256
XP_002308983  62 STCDLDnst----vqSQRS--ISSISLpnk---npaSSTGGMS---SNSEFVNHGLLLWQLSRLQWI-------GSGTSG 122
XP_002524505  62 STCDLEnsa----iqSQRS--VSSISVsna---nlcIGTSGTS---STSEFVNQGFLLWQQSRLQWT-------GNNNSR 122
XP_002455104  83 TTIEVEp-------aDLRG--VSPMSTsnw---afdQHGTGSSH--NLPGLGNNGLILWEQTRQEWT-------EIRSLR 141
XP_011272001 173 EENQLNiin----esSYEN--FDSVL----------EAKKLHKELGEDKPFIN-GEDIWQKRRNAWL-------YSNNEL 228
EMG50606     213 VYNDIDiielrkefeTWVN--NTNTLSdsdskstllSST-------------NIGTNLWEYRRSKWLnntnpisISNNEE 277
XP_002547160 216 LFHDIDiielrkefeTWVN--SKST-TdtdskstllSQS-------------NIGSNLWEYRRSKWL-------QCDDPN 272
CCE84299     164 SFQDLDvcelrelwdAYVA--QGAPETddskvailkDELPSLESIDTN----NIGEKLWELRRSKWL-------AKDADS 230
XP_001384632 219 NFRDLDlcklkqefeIHAK--NESPAM---------DSGSSRTTLHMNLQIDNIGTSLWEYRRSKWL-------ANDDPQ 280
Q6BS68       190 sYHDVDickmredlsLLLKqiVSSESIadtskstlrERGSQI----------NLGEMLWEYRRSKWL-------ITNPEG 252 Debaryomyces ha...

EPE07745     257 VK--PAKP---IvssspssprrslfrfhshsksqqvatpavsipatiasstatvSspapvlplspvmsnsrhsqysqqsh 331
XP_002308983 123 NQ--NQRRqe---------------------------------------------------------------------- 130
XP_002524505 123 GK--THYRle---------------------------------------------------------------------- 130
XP_002455104 142 PK--VKQVre---------------------------------------------------------------------- 149
XP_011272001 229 KS--KAKQrslDn-----------------------------------------S------------------------- 240
EMG50606     278 KL--KKRLre---------------------------------------------------------------------- 285
XP_002547160 273 KL--NNRLkq---------------------------------------------------------------------- 280
CCE84299     231 DKklEHRIee---------------------------------------------------------------------- 240
XP_001384632 281 KV--EKRLrk---------------------------------------------------------------------- 288
Q6BS68       253 ELraEEHLrq---------------------------------------------------------------------- 262 Debaryomyces ha...

EPE07745     332 qtqqsrnsqqsagldtvattpitsddgaegvdgaggallhlaisntapikptrsratqgssrrissnqpgfvqhpeyave 411
XP_002308983     --------------------------------------------------------------------------------    
XP_002524505     --------------------------------------------------------------------------------    
XP_002455104     --------------------------------------------------------------------------------    
XP_011272001     --------------------------------------------------------------------------------    
EMG50606         --------------------------------------------------------------------------------    
XP_002547160     --------------------------------------------------------------------------------    
CCE84299         --------------------------------------------------------------------------------    
XP_001384632     --------------------------------------------------------------------------------    
Q6BS68           --------------------------------------------------------------------------------     Debaryomyces ha...

EPE07745     412 tlvpvshpllppnnpMRQSITPALYLSLYDKLVTGLTPPS--CPINLSDMIRSCVAGWKRDNEWP 474
XP_002308983 131 --------------------sRLSWNATYEGLLGSRNPFP--KPIPLSEMVNFLVDVWEQEGLYD 173
XP_002524505 131 --------------------hRLSWNATYEGLLGSRNPFR--RPIPLSEMVDFLVDIWEQEGLYD 173
XP_002455104 150 --------------------pVLSWNAAYESLLGSNKPFP--QPIPLHEMVDFLVDIWEQEGLYD 192
XP_011272001 241 ----------------LVGISKDNYPIIYNSLIEKQKTLK--KPMNLKDALKVINAGWIASKKWE 287
EMG50606     286 --------------tSISYIPKESYIKIYSSLIDKNKVLRndKHINLSDLIKIMNIGWIAEDKWE 336
XP_002547160 281 --------------tSISYIPKDSYVQIYSSLIDKNKTLKndKHINLSDLLKIINAGWIAEDKWE 331
CCE84299     241 --------------mSISHIPRESYARIYCNLVDKEKPLKggRRLNLADLIQVINAGWIAEERWE 291
XP_001384632 289 --------------sSISHIPRDLYVKIYNNLVDKGRLLKneKRINLEDLVKIINAGWIAEEKWE 339
Q6BS68       263 --------------lSIAHIPKNSYVRIYNNLVDKGRLLKddKRINLSDLIKVINAGWIAEERWD 313 Debaryomyces hansenii
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