pfam13234: MTR4_beta-barrel (This model is not part of the current CDD release)
Mtr4-like, beta-barrel domain
Exosome RNA helicase Mtr4 is a essential RNA helicase, and is an exosome-activating cofactor. It functions together with the nuclear exosome being involved in processing of structured RNAs, including snRNAs and snoRNAs. It also plays a role in nuclear RNA surveillance pathways involving the so-called TRAMP complex. It contains an arch domain, required for proper 5.8S rRNA processing, and appears to function independently of canonical helicase activity. The arch domain comprises an helical stalk/elbow that flanks a KOW module which adopts a beta-barrel fold. This entry represents the beta-barrel of MTR4 and related Ski2-like helicases. Ski2 from yeast has an overall similar structure to MTR4 proteins. However, it does not have the KOW motif and it is not included in this entry.
Jiyao W et al.(2023). "The conserved domain database in 2023.",