Conserved Protein Domain Family
Fer4_8

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pfam13183: Fer4_8 (This model is not part of the current CDD release)
4Fe-4S dicluster domain
Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.
Statistics
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PSSM-Id: 520603
Aligned: 128 rows
Threshold Bit Score: 28.0469
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5ZV08        570 NCNGNGACFdyk--lqdVM-----C------PSYKISR-D-RIHSPKGRASL----VREWLRQlsaltgkreltwplkkr 630  Legionella pn...
WP_012107588  294 PCTGCRYCT--------P------CengvgiPECFEFY-N-QAHIYDAKEHAggiyGWALSGIfgg-------------- 343  Methanoregula...
WP_012446804  297 GCTDCRYCL--------P------Cepe-niPISSIFNlYnELHLFKDQDKA----KQTYQKLidg-------------- 343  Natranaerobiu...
Q2JKQ7        277 RCTQCYACL--------P------CpegihiPEVLRLR-N-LAIAHEMTEFAqyryNMFGQAGhwf-------------- 326  Synechococcus...
Q8YLN6        262 QCSQCYACL--------P------CpeniniPEVLRLR-N-LAVAYNMTDYGqyryGMFENAGhwf-------------- 311  Nostoc sp. PC...
BAF60867      258 FCRRCEYCQ--------P------CpvgidiPTVFLLD-G-YYRRYDLKGWAiqryNAMKVK------------------ 303 
WP_012610029  258 FCHRCGYCL--------P------CeqgvmiPESLMFR-P-IIHRLGEAIAVamskPAVSGI------------------ 303  Desulfatibaci...
WP_015918696   17 SCTRCTFCKwvp--evrSQdfaeiC------PSVQHGK-F-FSHTAGGKLIAayalLHNRVEYtpd-------------- 72   Rhizobium/Agr...
WP_015948773   12 HCHRCSYCKfipfqlikSKrfsylC------PSISLRN-F-HSFSAGGRAALglavVEGRLDEytem------------- 70   Desulfatibaci...
WP_015906461   24 YCINCRFCL--------PS-----C------PLFNITS-G-EISHGGSGITRslyyAVQWGLEdketl------------ 70   Desulforapulu...
Q5ZV08        631 lntykrnhgqydfshevytALEGCLGCHACRSQCPV----NI 668  Legionella pneumophila subsp. pneumophila str. Phil...
WP_012107588  344 ----------------ipaYASCCTECGACEEKCPQ----GL 365  Methanoregula boonei
WP_012446804  344 -----------------erDGGRCIECGACEQECPQ----DI 364  Natranaerobius thermophilus
Q2JKQ7        327 ----------------pgsLADRCTECGDCLPRCPE----HL 348  Synechococcus sp. JA-2-3B'a(2-13)
Q8YLN6        312 ----------------pgmKANRCTECGDCLPRCPE----NL 333  Nostoc sp. PCC 7120
BAF60867      304 --------------------PGACKECGACEEKCPY----NL 321 
WP_012610029  304 ---------------------EECTQCGECAERCPY----GL 320  Desulfatibacillum aliphaticivorans
WP_015918696   73 ----------------fiqNVYSCSMCGGCDTSCKTlladFV 98   Rhizobium/Agrobacterium group
WP_015948773   71 ----------------mkqIVFECTMCGACQVQCRTfn-fNL 95   Desulfatibacillum aliphaticivorans
WP_015906461   71 --------------helrdILYECTTCGSCELACKNls-tGT 97   Desulforapulum autotrophicum
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